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    scrn3 secernin 3 [ Danio rerio (zebrafish) ]

    Gene ID: 326058, updated on 4-Jan-2025

    Summary

    Official Symbol
    scrn3provided by ZNC
    Official Full Name
    secernin 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4783
    See related
    Ensembl:ENSDARG00000016611 AllianceGenome:ZFIN:ZDB-GENE-030131-4783
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55430; wu:fd60b06
    Summary
    Predicted to enable cysteine-type exopeptidase activity and dipeptidase activity. Predicted to act upstream of or within proteolysis. Orthologous to human SCRN3 (secernin 3). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See scrn3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (2561172..2572833, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (2510390..2522694, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene WAS/WASL interacting protein family, member 1a Neighboring gene G protein-coupled receptor 155a Neighboring gene corepressor interacting with RBPJ, CIR1 Neighboring gene sp9 transcription factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cysteine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables dipeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199738.1NP_956032.1  secernin-3

      See identical proteins and their annotated locations for NP_956032.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044168
      UniProtKB/Swiss-Prot
      Q803W1
      Related
      ENSDARP00000014414.7, ENSDART00000016710.9
      Conserved Domains (1) summary
      cl00467
      Location:5318
      Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      2561172..2572833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009304428.4XP_009302703.1  secernin-3 isoform X1

      UniProtKB/TrEMBL
      A0A8M3B5C8
      Conserved Domains (1) summary
      cl00467
      Location:17330
      Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...