gpd1b glycerol-3-phosphate dehydrogenase 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpd1bprovided by ZNC
Official Full Name: glycerol-3-phosphate dehydrogenase 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3906
See related: Ensembl:ENSDARG00000043180 AllianceGenome:ZFIN:ZDB-GENE-030131-3906
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Gpd1; gpd1h; gpd1l; zgc:66051; zgc:85742; wu:fc58b05
Summary: Predicted to enable NAD binding activity; glycerol-3-phosphate dehydrogenase (NAD+) activity; and protein homodimerization activity. Predicted to be involved in NADH oxidation and glycerol-3-phosphate metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including intermediate cell mass of mesoderm; neural plate; notochord; ventral mesoderm; and yolk syncytial layer. Orthologous to human GPD1 (glycerol-3-phosphate dehydrogenase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (6996046..7006925, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (6966200..6977079, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables glycerol-3-phosphate dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NADH oxidation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycerol-3-phosphate catabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol-3-phosphate catabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol-3-phosphate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glycerol-3-phosphate metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glycerol-3-phosphate dehydrogenase 1b

Names: glycerol-3-phosphate dehydrogenase 1 (soluble), like; glycerol-3-phosphate dehydrogenase 1h

NP_956000.1

EC 1.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199706.1 → NP_956000.1 glycerol-3-phosphate dehydrogenase 1b

See identical proteins and their annotated locations for NP_956000.1

Status: PROVISIONAL

Source sequence(s)

BC055382

UniProtKB/TrEMBL

Q7T1E0

Related

ENSDARP00000114396.1, ENSDART00000133143.2

Conserved Domains (3) summary

TIGR03376
Location:5 → 343

glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))

pfam01210
Location:5 → 171

NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus

pfam07479
Location:197 → 337

NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus