MagR Magnetic receptor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: MagRprovided by FlyBase
Official Full Name: Magnetic receptorprovided by FlyBase
Primary source: FLYBASE:FBgn0026666
Locus tag: Dmel_CG8198
See related: AllianceGenome:FB:FBgn0026666
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:AT26381; CG8198; dMagR; Dmel\CG8198; IscA1; l(1)G0136
Summary: Predicted to enable 2 iron, 2 sulfur cluster binding activity. Involved in response to magnetism. Predicted to be part of mitochondrial [4Fe-4S] assembly complex. Predicted to be active in mitochondrion. Is expressed in adult head. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 5. Orthologous to human ISCA1 (iron-sulfur cluster assembly 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (15734270..15735780)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (15628303..15629813)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IBA Inferred from Biological aspect of Ancestor more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in iron-sulfur cluster assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in iron-sulfur cluster assembly	IEA Inferred from Electronic Annotation more info
involved_in iron-sulfur cluster assembly	NAS Non-traceable Author Statement more info	PubMed
involved_in protein maturation by iron-sulfur cluster transfer	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to magnetism	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial [4Fe-4S] assembly complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrial matrix	NAS Non-traceable Author Statement more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

Names: CG8198-PA; CG8198-PB; IscA1 homologue; MagR-PA; MagR-PB; lethal (1) G0136; magnetoreceptor

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The following sections contain reference sequences that belong to a specific genome build. Explain