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    Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318981, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mgat3provided by FlyBase
    Official Full Name
    beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051849
    Locus tag
    Dmel_CG31849
    See related
    AllianceGenome:FB:FBgn0051849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD34806; CG31849; Dmel\CG31849; dMGAT3; MGAT
    Summary
    Predicted to enable glycosyltransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process. Predicted to be located in membrane. Is expressed in organism. Orthologous to human MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Mgat3 in Genome Data Viewer
    Location:
    34A8-34A8; 2-47 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13180398..13182596, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13180398..13182596, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Scm-related gene containing four mbt domains Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Alg7 dolichyl-phosphate N-acetylglucosaminephosphotransferase Neighboring gene uncharacterized protein Neighboring gene Radial spoke head protein 1 Neighboring gene ER degradation enhancer, mannosidase alpha-like 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diversity and functions of protein glycosylation in insects. Walski T, et al. Insect Biochem Mol Biol, 2017 Apr. PMID 28232040
    2. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Bellen HJ, et al. Genetics, 2004 Jun. PMID 15238527, Free PMC Article
    3. A journey into the world of insect lipid metabolism. Toprak U, et al. Arch Insect Biochem Physiol, 2020 Jun. PMID 32335968
    4. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
    Names
    CG31849-PA
    Mgat3-PA
    NP_723787.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13180398..13182596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165027.2 → NP_723787.1  beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RF3
      Related
      FBpp0080068
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95RF3 Q95RF3

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