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    Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316435, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cyp20a1provided by RGD
    Official Full Name
    cytochrome P450, family 20, subfamily a, polypeptide 1provided by RGD
    Primary source
    RGD:735221
    See related
    EnsemblRapid:ENSRNOG00000017631 AllianceGenome:RGD:735221
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. Orthologous to human CYP20A1 (cytochrome P450 family 20 subfamily A member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 139.2), Heart (RPKM 127.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cyp20a1 in Genome Data Viewer
    Location:
    9q32
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (69249841..69299146)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (61755804..61805123)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (67130222..67179693)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene neurobeachin-like 1 Neighboring gene peptidyl-prolyl cis-trans isomerase NIMA-interacting 4-like Neighboring gene ATP synthase membrane subunit c locus 2, pseudogene 1 Neighboring gene abl-interactor 2 Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Neighboring gene uncharacterized LOC102547711

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 20A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199401.1 → NP_955433.1  cytochrome P450 20A1

      See identical proteins and their annotated locations for NP_955433.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061716
      UniProtKB/Swiss-Prot
      Q6P7D4
      UniProtKB/TrEMBL
      F1LSK6
      Related
      ENSRNOP00000023796.4, ENSRNOT00000023796.6
      Conserved Domains (1) summary
      cl12078
      Location:43 → 415
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      69249841..69299146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017596467.3 → XP_017451956.1  cytochrome P450 20A1 isoform X1

      Conserved Domains (1) summary
      cl41757
      Location:1 → 355
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. XM_017596468.3 → XP_017451957.1  cytochrome P450 20A1 isoform X1

      Conserved Domains (1) summary
      cl41757
      Location:1 → 355
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    3. XM_039083641.2 → XP_038939569.1  cytochrome P450 20A1 isoform X2

      Conserved Domains (1) summary
      cl41757
      Location:1 → 229
      cytochrome_P450; cytochrome P450 (CYP) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P7D4.1 GenPept UniProtKB/Swiss-Prot:Q6P7D4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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