Dnaaf6 dynein axonemal assembly factor 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dnaaf6provided by RGD
Official Full Name: dynein axonemal assembly factor 6provided by RGD
Primary source: RGD:1566312
See related: EnsemblRapid:ENSRNOG00000054900 AllianceGenome:RGD:1566312
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Pih1d3
Summary: Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in flagellated sperm motility; inner dynein arm assembly; and outer dynein arm assembly. Predicted to be located in trans-Golgi network. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 36. Orthologous to human DNAAF6 (dynein axonemal assembly factor 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Lung (RPKM 14.7), Testes (RPKM 6.2) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq32

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (108513002..108564204)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (103724419..103775633)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (111389557..111439399)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables dynein intermediate chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables dynein intermediate chain binding	ISO Inferred from Sequence Orthology more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in axonemal dynein complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in axonemal dynein complex assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium movement	ISO Inferred from Sequence Orthology more info
involved_in flagellated sperm motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in flagellated sperm motility	ISO Inferred from Sequence Orthology more info
involved_in inner dynein arm assembly	ISO Inferred from Sequence Orthology more info
involved_in outer dynein arm assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: dynein axonemal assembly factor 6

Names: PIH1 domain containing 3; dynein assembly factor 6, axonemal

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.