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    Mfsd13a major facilitator superfamily domain containing 13A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309454, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mfsd13aprovided by RGD
    Official Full Name
    major facilitator superfamily domain containing 13Aprovided by RGD
    Primary source
    RGD:1309313
    See related
    EnsemblRapid:ENSRNOG00000019674 AllianceGenome:RGD:1309313
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem180; RGD1309313
    Summary
    Predicted to be located in plasma membrane. Orthologous to human MFSD13A (major facilitator superfamily domain containing 13A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 30.5), Adrenal (RPKM 21.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mfsd13a in Genome Data Viewer
    Location:
    1q54
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (255158338..255177731)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (245216610..245236314)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (266097293..266122359)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene CUE domain containing 2 Neighboring gene similar to human chromosome 10 open reading frame 95 Neighboring gene microRNA 146b Neighboring gene actin related protein 1A Neighboring gene uncharacterized LOC134484078 Neighboring gene SUFU negative regulator of hedgehog signaling

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 180

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001393812.1 → NP_001380741.1  transmembrane protein 180

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZRA8, A6JHM3, F7EKD2
      Related
      ENSRNOP00000081136.1, ENSRNOT00000100851.2
      Conserved Domains (1) summary
      cd17481
      Location:17 → 500
      MFS_MFSD13A; Major facilitator superfamily domain containing 13A

    RNA

    1. NR_172015.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      255158338..255177731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264998.1 → XP_063121068.1  transmembrane protein 180 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JUB6, A0A8I5ZRA8
      Related
      ENSRNOP00000100244.1, ENSRNOT00000143398.1

    2. XM_017589292.3 → XP_017444781.1  transmembrane protein 180 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JUB6, A0A8I5ZRA8

    3. XM_063265015.1 → XP_063121085.1  transmembrane protein 180 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRA8, A6JHM3, F7EKD2

    4. XM_008760432.4 → XP_008758654.1  transmembrane protein 180 isoform X2

      See identical proteins and their annotated locations for XP_008758654.1

      UniProtKB/TrEMBL
      A0A8I5ZRA8, A6JHM3, F7EKD2
      Related
      ENSRNOP00000069037.3, ENSRNOT00000088243.3
      Conserved Domains (1) summary
      cd17481
      Location:17 → 500
      MFS_MFSD13A; Major facilitator superfamily domain containing 13A

    5. XM_017589293.3 → XP_017444782.2  transmembrane protein 180 isoform X3

      Conserved Domains (1) summary
      cl28910
      Location:51 → 412
      MFS; Major Facilitator Superfamily

    6. XM_063265024.1 → XP_063121094.1  transmembrane protein 180 isoform X5

    7. XM_063265030.1 → XP_063121100.1  transmembrane protein 180 isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y5X5
      Related
      ENSRNOP00000077101.1, ENSRNOT00000103197.2

    8. XM_063265034.1 → XP_063121104.1  transmembrane protein 180 isoform X7

      UniProtKB/TrEMBL
      A0A8I6A1V0, Q5XI40
      Related
      ENSRNOP00000049314.5, ENSRNOT00000043925.6

    9. XM_063265007.1 → XP_063121077.1  transmembrane protein 180 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRA8, A6JHM3, F7EKD2
      Related
      ENSRNOP00000084701.2, ENSRNOT00000109666.2

    10. XM_063265013.1 → XP_063121083.1  transmembrane protein 180 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRA8, A6JHM3, F7EKD2

    11. XM_063265019.1 → XP_063121089.1  transmembrane protein 180 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZRA8
    Nucleotide Protein Strain
    Heading Accession and Version

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