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    Abhd15 abhydrolase domain containing 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303343, updated on 9-Dec-2024

    Summary

    Official Symbol
    Abhd15provided by RGD
    Official Full Name
    abhydrolase domain containing 15provided by RGD
    Primary source
    RGD:1304598
    See related
    EnsemblRapid:ENSRNOG00000015002 AllianceGenome:RGD:1304598
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304598
    Summary
    Predicted to enable monoacylglycerol lipase activity and short-chain carboxylesterase activity. Predicted to be involved in adipose tissue development; cellular lipid metabolic process; and lipid catabolic process. Orthologous to human ABHD15 (abhydrolase domain containing 15). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 34.7), Adrenal (RPKM 32.6) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Abhd15 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (62861335..62866726)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (62363209..62368600)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (62643453..62648844, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene GIT ArfGAP 1 Neighboring gene tumor protein p53 inducible protein 13 Neighboring gene TAO kinase 1 Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables short-chain carboxylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in adipose tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lipid catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein ABHD15
    Names
    abhydrolase domain-containing protein 15
    alpha/beta hydrolase-1
    lung alpha/beta hydrolase 1
    NP_001100495.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107025.1NP_001100495.1  protein ABHD15 precursor

      See identical proteins and their annotated locations for NP_001100495.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HGY5, D3Z8B6
      Related
      ENSRNOP00000036157.4, ENSRNOT00000034282.6
      Conserved Domains (1) summary
      cl21494
      Location:85410
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      62861335..62866726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)