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    Ifna2 interferon alpha 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298213, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ifna2provided by RGD
    Official Full Name
    interferon alpha 2provided by RGD
    Primary source
    RGD:1311425
    See related
    EnsemblRapid:ENSRNOG00000078310 AllianceGenome:RGD:1311425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    If1ai9
    Summary
    Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Crimean-Congo hemorrhagic fever; common cold; hepatitis B; liver disease (multiple); and sarcoidosis. Orthologous to several human genes including IFNA1 (interferon alpha 1); IFNA10 (interferon alpha 10); and IFNA13 (interferon alpha 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Ifna2 in Genome Data Viewer
    Location:
    5q32
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (108374363..108374941, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (103258617..103259195, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (107416117..107416695, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene interferon, alpha 16-like 1 Neighboring gene interferon alpha-1-like Neighboring gene interferon alpha-1-like Neighboring gene interferon alpha-1-like Neighboring gene interferon, alpha 4 like 2

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from PubChem

    General protein information

    Preferred Names
    interferon alpha family, gene 2
    Names
    interferon 1ai9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271218.1NP_001258147.1  interferon alpha family, gene 2 precursor

      See identical proteins and their annotated locations for NP_001258147.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A0G2K3I2
      Related
      ENSRNOP00000106016.1, ENSRNOT00000170823.1
      Conserved Domains (1) summary
      pfam00143
      Location:26185
      Interferon; Interferon alpha/beta domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      108374363..108374941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)