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    Znhit2 zinc finger, HIT domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 29805, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Znhit2provided by MGI
    Official Full Name
    zinc finger, HIT domain containing 2provided by MGI
    Primary source
    MGI:MGI:1352481
    See related
    Ensembl:ENSMUSG00000075227 AllianceGenome:MGI:1352481
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fon; ORF6; C11orf5; Znhit2-ps
    Summary
    Predicted to enable metal ion binding activity. Is expressed in several structures, including liver; renal cortex; seminiferous tubule; telencephalon; and thymus. Orthologous to human ZNHIT2 (zinc finger HIT-type containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human all
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    Genomic context

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    See Znhit2 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6111237..6112498)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6061207..6062468)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene synovial apoptosis inhibitor 1, synoviolin Neighboring gene mitochondrial ribosomal protein L49 Neighboring gene STARR-seq mESC enhancer starr_45418 Neighboring gene FAU ubiquitin like and ribosomal protein S30 fusion Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 GARP complex subunit Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:6077181-6077364 Neighboring gene transmembrane protein 262 Neighboring gene zinc finger like protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of human and murine C11orf5, a new member of the FAUNA gene cluster. Lemmens IH, et al. Mamm Genome, 2000 Jan. PMID 10602999
    2. Overlapping peri-implantation phenotypes of ZNHIT1 and ZNHIT2 despite distinct functions during early mouse development†. He XD, et al. Biol Reprod, 2024 Nov 11. PMID 39194072,
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger HIT domain-containing protein 2
    Names
    zinc finger, HIT domain containing 2, pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013859.2 → NP_038887.2  zinc finger HIT domain-containing protein 2

      See identical proteins and their annotated locations for NP_038887.2

      Status: VALIDATED

      Source sequence(s)
      AK086863
      Consensus CDS
      CCDS57131.1
      UniProtKB/Swiss-Prot
      Q8C356, Q8VCQ7, Q9QY66
      UniProtKB/TrEMBL
      Q569Y3
      Related
      ENSMUSP00000134031.3, ENSMUST00000162726.5
      Conserved Domains (1) summary
      pfam04438
      Location:3 → 36
      zf-HIT; HIT zinc finger

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      6111237..6112498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QY66.2 GenPept UniProtKB/Swiss-Prot:Q9QY66

    Gene LinkOut

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