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    mrpl11 mitochondrial ribosomal protein L11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293666, updated on 9-Dec-2024

    Summary

    Symbol
    mrpl11provided by RGD
    Full Name
    mitochondrial ribosomal protein L11provided by RGD
    Primary source
    RGD:1359665
    See related
    EnsemblRapid:ENSRNOG00000019970 AllianceGenome:RGD:1359665
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL11 (mitochondrial ribosomal protein L11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 316.2), Muscle (RPKM 243.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See mrpl11 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (211693807..211696667)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202264419..202267288)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220243469..220246340)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099977 Neighboring gene dipeptidylpeptidase 3 Neighboring gene pellino E3 ubiquitin protein ligase family member 3 Neighboring gene neuronal PAS domain protein 4 Neighboring gene small nucleolar RNA SNORA48

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC94654

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein uL11m
    Names
    39S ribosomal protein L11, mitochondrial
    L11mt
    MRP-L11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006973.2NP_001006974.2  large ribosomal subunit protein uL11m

      Status: VALIDATED

      Source sequence(s)
      FM054141, FM108602, FM109142, JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q5XIE3
      UniProtKB/TrEMBL
      A0A0G2JYU2, A6HZ10
      Related
      ENSRNOP00000070790.1, ENSRNOT00000084650.3
      Conserved Domains (1) summary
      smart00649
      Location:20156
      RL11; Ribosomal protein L11/L12

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      211693807..211696667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)