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    Rpl36a ribosomal protein L36A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292964, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rpl36aprovided by RGD
    Official Full Name
    ribosomal protein L36Aprovided by RGD
    Primary source
    RGD:1306640
    See related
    EnsemblRapid:ENSRNOG00000075816 AllianceGenome:RGD:1306640
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL36A (ribosomal protein L36a). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 1557.7), Thymus (RPKM 1449.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rpl36a in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (102058573..102062162)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (97766179..97768892)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (105402867..105405580)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene transfer RNA aspartic acid (anticodon AUC) 1 Neighboring gene translocase of inner mitochondrial membrane 8A1 Neighboring gene Bruton tyrosine kinase Neighboring gene galactosidase, alpha Neighboring gene heterogeneous nuclear ribonucleoprotein H2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Primary structure of rat ribosomal protein L36a. Gallagher MJ, et al. DNA, 1988 May. PMID 3396452
    2. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, et al. J Biol Chem, 1977 Jun 10. PMID 863909
    3. Structural snapshots of actively translating human ribosomes. Behrmann E, et al. Cell, 2015 May 7. PMID 25957688, Free PMC Article
    4. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. Odintsova TI, et al. J Protein Chem, 2003 Apr. PMID 12962325
    5. Structures of the human and Drosophila 80S ribosome. Anger AM, et al. Nature, 2013 May 2. PMID 23636399

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC188784

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL42
    Names
    60S ribosomal protein L36a
    60S ribosomal protein L44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128065.1 → NP_001121537.1  large ribosomal subunit protein eL42

      See identical proteins and their annotated locations for NP_001121537.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473969
      UniProtKB/Swiss-Prot
      P83883
      UniProtKB/TrEMBL
      B2RYQ8, F8WFR5
      Related
      ENSRNOP00000111029.1, ENSRNOT00000149159.1
      Conserved Domains (1) summary
      PTZ00157
      Location:1 → 86
      PTZ00157; 60S ribosomal protein L36a; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      102058573..102062162
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279831.1 → XP_063135901.1  large ribosomal subunit protein eL42 isoform X3

      UniProtKB/TrEMBL
      F8WFR5

    2. XM_063279829.1 → XP_063135899.1  large ribosomal subunit protein eL42 isoform X1

    3. XM_063279830.1 → XP_063135900.1  large ribosomal subunit protein eL42 isoform X2

      UniProtKB/TrEMBL
      F8WFR5
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P83883.2 GenPept UniProtKB/Swiss-Prot:P83883

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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