Slc27a6 solute carrier family 27 member 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Slc27a6provided by RGD
Full Name: solute carrier family 27 member 6provided by RGD
Primary source: RGD:1311977
See related: EnsemblRapid:ENSRNOG00000058193 AllianceGenome:RGD:1311977
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable long-chain fatty acid transmembrane transporter activity; long-chain fatty acid-CoA ligase activity; and very long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid import into cell and long-chain fatty acid metabolic process. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Biomarker of myocardial infarction. Orthologous to human SLC27A6 (solute carrier family 27 member 6). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 214.3), Lung (RPKM 85.2) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 18q12.1

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (54238697..54297595)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (52040241..52099622)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (53609497..53667833)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables long-chain fatty acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid-CoA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables very long-chain fatty acid-CoA ligase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in long-chain fatty acid import into cell	IBA Inferred from Biological aspect of Ancestor more info
involved_in long-chain fatty acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: long-chain fatty acid transport protein 6

Names: long-chain fatty acid transport protein 6-like; solute carrier family 27 (fatty acid transporter), member 6

NP_001099615.1

EC 6.2.1.15

XP_038952625.1

EC 6.2.1.15

XP_038952626.1

EC 6.2.1.15

XP_063133282.1

EC 6.2.1.15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106145.1 → NP_001099615.1 long-chain fatty acid transport protein 6

See identical proteins and their annotated locations for NP_001099615.1

Status: PROVISIONAL

Source sequence(s)

CH473971

UniProtKB/TrEMBL

A6IX92, D4A2B8

Related

ENSRNOP00000069400.1, ENSRNOT00000077443.3

Conserved Domains (1) summary

cl17068
Location:75 → 609

AFD_class_I; Adenylate forming domain, Class I superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086036.1 Reference GRCr8

Range

54238697..54297595

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063277212.1 → XP_063133282.1 long-chain fatty acid transport protein 6 isoform X3
XM_039096697.2 → XP_038952625.1 long-chain fatty acid transport protein 6 isoform X1

Conserved Domains (1) summary

cl17068
Location:75 → 487

AFD_class_I; Adenylate forming domain, Class I superfamily
XM_039096698.2 → XP_038952626.1 long-chain fatty acid transport protein 6 isoform X2

Conserved Domains (1) summary

cl17068
Location:38 → 365

AFD_class_I; Adenylate forming domain, Class I superfamily