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    Etl4 enhancer trap locus 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291356, updated on 27-Nov-2024

    Summary

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    Symbol
    Etl4provided by RGD
    Full Name
    enhancer trap locus 4provided by RGD
    Primary source
    RGD:1563437
    See related
    EnsemblRapid:ENSRNOG00000008666 AllianceGenome:RGD:1563437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563437
    Summary
    Predicted to be involved in embryonic skeletal system development. Predicted to be located in centrosome. Predicted to be active in cytoplasm. Orthologous to human KIAA1217 (KIAA1217). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 136.9), Heart (RPKM 84.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Etl4 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (87749486..88213158)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (82841075..83304868)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (87173265..87681268)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L37-like Neighboring gene U6 spliceosomal RNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like Neighboring gene uncharacterized LOC120097745 Neighboring gene Rho GTPase activating protein 21 Neighboring gene uncharacterized LOC102550154

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc. Semba K, et al. Genetics, 2006 Jan. PMID 16204209, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in embryonic skeletal system development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    sickle tail protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427790.1 → NP_001414719.1  sickle tail protein homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I5YBN1
      Related
      ENSRNOP00000077128.1, ENSRNOT00000116431.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      87749486..88213158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276268.1 → XP_063132338.1  sickle tail protein homolog isoform X1

    2. XM_008771907.4 → XP_008770129.3  sickle tail protein homolog isoform X7

      UniProtKB/TrEMBL
      A0A8I6GEH8
      Conserved Domains (2) summary
      pfam03915
      Location:237 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:693 → 952
      pneumo_PspA; pneumococcal surface protein A

    3. XM_039096217.2 → XP_038952145.1  sickle tail protein homolog isoform X2

      UniProtKB/TrEMBL
      A0A8I6GEH8
      Conserved Domains (2) summary
      pfam03915
      Location:237 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:728 → 987
      pneumo_PspA; pneumococcal surface protein A

    4. XM_063276269.1 → XP_063132339.1  sickle tail protein homolog isoform X5

    5. XM_039096218.2 → XP_038952146.1  sickle tail protein homolog isoform X3

      UniProtKB/TrEMBL
      A0A8I6GEH8
      Related
      ENSRNOP00000086860.1, ENSRNOT00000114046.2
      Conserved Domains (2) summary
      pfam03915
      Location:237 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:728 → 987
      pneumo_PspA; pneumococcal surface protein A

    6. XM_063276270.1 → XP_063132340.1  sickle tail protein homolog isoform X6

    7. XM_039096229.2 → XP_038952157.1  sickle tail protein homolog isoform X22

      UniProtKB/TrEMBL
      A0A8I6A455
      Conserved Domains (2) summary
      pfam03915
      Location:237 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:728 → 987
      pneumo_PspA; pneumococcal surface protein A

    8. XM_039096227.2 → XP_038952155.1  sickle tail protein homolog isoform X21

      UniProtKB/TrEMBL
      A6JMB1
      Conserved Domains (2) summary
      pfam03915
      Location:237 → 315
      AIP3; Actin interacting protein 3
      NF033930
      Location:693 → 952
      pneumo_PspA; pneumococcal surface protein A

    9. XM_039096230.2 → XP_038952158.1  sickle tail protein homolog isoform X24

      UniProtKB/TrEMBL
      A0A8I6A4F8, A6JMB1
      Related
      ENSRNOP00000085969.1, ENSRNOT00000096341.2
      Conserved Domains (2) summary
      pfam03915
      Location:188 → 266
      AIP3; Actin interacting protein 3
      NF033930
      Location:644 → 903
      pneumo_PspA; pneumococcal surface protein A

    10. XM_039096219.2 → XP_038952147.1  sickle tail protein homolog isoform X4

      UniProtKB/TrEMBL
      M0R5H1
      Related
      ENSRNOP00000064638.3, ENSRNOT00000073718.5
      Conserved Domains (2) summary
      pfam03915
      Location:215 → 293
      AIP3; Actin interacting protein 3
      NF033930
      Location:706 → 965
      pneumo_PspA; pneumococcal surface protein A

    11. XM_063276271.1 → XP_063132341.1  sickle tail protein homolog isoform X8

    12. XM_039096221.2 → XP_038952149.1  sickle tail protein homolog isoform X9

      UniProtKB/TrEMBL
      M0R5H1
      Conserved Domains (2) summary
      pfam03915
      Location:188 → 266
      AIP3; Actin interacting protein 3
      NF033930
      Location:644 → 903
      pneumo_PspA; pneumococcal surface protein A

    13. XM_039096222.2 → XP_038952150.1  sickle tail protein homolog isoform X10

      UniProtKB/TrEMBL
      A0A8I6A6M2, M0R5H1
      Related
      ENSRNOP00000086839.1, ENSRNOT00000096762.2
      Conserved Domains (2) summary
      pfam03915
      Location:188 → 266
      AIP3; Actin interacting protein 3
      NF033930
      Location:644 → 903
      pneumo_PspA; pneumococcal surface protein A

    14. XM_063276281.1 → XP_063132351.1  sickle tail protein homolog isoform X23

    15. XM_039096231.2 → XP_038952159.1  sickle tail protein homolog isoform X25

      UniProtKB/TrEMBL
      A0A8I6A455
      Related
      ENSRNOP00000087978.2, ENSRNOT00000107420.2
      Conserved Domains (2) summary
      pfam03915
      Location:188 → 266
      AIP3; Actin interacting protein 3
      NF033930
      Location:679 → 938
      pneumo_PspA; pneumococcal surface protein A

    16. XM_039096223.2 → XP_038952151.1  sickle tail protein homolog isoform X11

      UniProtKB/TrEMBL
      M0R5H1
      Conserved Domains (2) summary
      pfam03915
      Location:104 → 182
      AIP3; Actin interacting protein 3
      NF033930
      Location:595 → 854
      pneumo_PspA; pneumococcal surface protein A

    17. XM_063276272.1 → XP_063132342.1  sickle tail protein homolog isoform X12

    18. XM_039096224.2 → XP_038952152.1  sickle tail protein homolog isoform X13

      UniProtKB/TrEMBL
      M0R5H1
      Conserved Domains (2) summary
      pfam03915
      Location:38 → 116
      AIP3; Actin interacting protein 3
      NF033930
      Location:529 → 788
      pneumo_PspA; pneumococcal surface protein A

    19. XM_063276280.1 → XP_063132350.1  sickle tail protein homolog isoform X20

    20. XM_063276275.1 → XP_063132345.1  sickle tail protein homolog isoform X16

    21. XM_039096225.2 → XP_038952153.1  sickle tail protein homolog isoform X14

      UniProtKB/TrEMBL
      M0R5H1
      Conserved Domains (1) summary
      NF033930
      Location:397 → 656
      pneumo_PspA; pneumococcal surface protein A

    22. XM_063276273.1 → XP_063132343.1  sickle tail protein homolog isoform X15

    23. XM_063276276.1 → XP_063132346.1  sickle tail protein homolog isoform X17

    24. XM_063276279.1 → XP_063132349.1  sickle tail protein homolog isoform X19

    25. XM_063276284.1 → XP_063132354.1  sickle tail protein homolog isoform X28

      Related
      ENSRNOP00000092656.1, ENSRNOT00000102713.2

    26. XM_063276282.1 → XP_063132352.1  sickle tail protein homolog isoform X26

    27. XM_063276278.1 → XP_063132348.1  sickle tail protein homolog isoform X18

    28. XM_039096226.2 → XP_038952154.1  sickle tail protein homolog isoform X14

      UniProtKB/TrEMBL
      M0R5H1
      Conserved Domains (1) summary
      NF033930
      Location:397 → 656
      pneumo_PspA; pneumococcal surface protein A

    29. XM_063276274.1 → XP_063132344.1  sickle tail protein homolog isoform X15

    30. XM_063276277.1 → XP_063132347.1  sickle tail protein homolog isoform X17

    31. XM_063276283.1 → XP_063132353.1  sickle tail protein homolog isoform X27

    Nucleotide Protein Strain
    Heading Accession and Version

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