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    PPP3R1 protein phosphatase 3 regulatory subunit B, alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 282321, updated on 10-Oct-2024

    Summary

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    Official Symbol
    PPP3R1provided by VGNC
    Official Full Name
    protein phosphatase 3 regulatory subunit B, alphaprovided by VGNC
    Primary source
    VGNC:VGNC:50247
    See related
    BGD:BT30320; Ensembl:ENSBTAG00000010619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PPP3R1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (66605841..66667488, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 10 Neighboring gene partner of NOB1 homolog Neighboring gene cannabinoid receptor interacting protein 1 Neighboring gene pleckstrin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of a cDNA clone coding for the calcium-binding subunit of calcineurin from bovine brain: an identical amino acid sequence to the human protein. Nargang CE, et al. DNA Seq, 1994. PMID 7803816
    2. The structure of the B subunit of calcineurin. Aitken A, et al. Eur J Biochem, 1984 Mar 15. PMID 6321184
    3. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Klee CB, et al. Proc Natl Acad Sci U S A, 1979 Dec. PMID 293720, Free PMC Article
    4. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Liu J, et al. Cell, 1991 Aug 23. PMID 1715244
    5. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Griffith JP, et al. Cell, 1995 Aug 11. PMID 7543369

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent protein serine/threonine phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcineurin subunit B type 1
    Names
    calcineurin B
    protein phosphatase 2B regulatory subunit 1
    NP_777008.1
    XP_059747007.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174583.2 → NP_777008.1  calcineurin subunit B type 1

      See identical proteins and their annotated locations for NP_777008.1

      Status: PROVISIONAL

      Source sequence(s)
      X71666
      UniProtKB/Swiss-Prot
      P63099
      UniProtKB/TrEMBL
      A0AAA9TX86
      Related
      ENSBTAP00000102960.1, ENSBTAT00000125997.1
      Conserved Domains (1) summary
      COG5126
      Location:13 → 157
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      66605841..66667488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891024.1 → XP_059747007.1  calcineurin subunit B type 1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P63099.2 GenPept UniProtKB/Swiss-Prot:P63099

    Gene LinkOut

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