p38c p38c MAP kinase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: p38cprovided by FlyBase
Official Full Name: p38c MAP kinaseprovided by FlyBase
Primary source: FLYBASE:FBgn0267339
Locus tag: Dmel_CG33338
See related: AllianceGenome:FB:FBgn0267339
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG33338; Dmel\CG33338; dMPK2B; dp38c; Dp38c; Mpk2B; p38; P38; P38c; p38MAPK; p38[MAPK]
Summary: Enables MAP kinase activity. Involved in several processes, including p38MAPK cascade; regulation of adult chitin-containing cuticle pigmentation; and regulation of response to oxidative stress. Located in cytoplasm. Orthologous to human MAPK12 (mitogen-activated protein kinase 12) and MAPK13 (mitogen-activated protein kinase 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (24149020..24150203, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (19974742..19975925, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables MAP kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables MAP kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in p38MAPK cascade	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in regulation of adult chitin-containing cuticle pigmentation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of lipid storage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of response to oxidative stress	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

NP_996277.1

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The following sections contain reference sequences that belong to a specific genome build. Explain