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    pnu1 endodeoxyribonuclease Pnu1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542291, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pnu1
    Official Full Name
    endodeoxyribonuclease Pnu1
    Primary source
    PomBase:SPAC17C9.08
    Locus tag
    SPOM_SPAC17C9.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    end1; nuc1
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    Genomic context

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    See pnu1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (4484695..4486032, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene zf-C2H2 type zinc finger protein/UBA domain protein Neighboring gene G-protein-coupled receptor Stm1 Neighboring gene ncRNA Neighboring gene TIM22 inner membrane protein import complex subunit Tim13 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dolichyl glucosyltransferase Alg8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The end1 gene of Schizosaccharomyces pombe coding for a DNase is identical with the pnu1 gene coding for an RNase. Sakem B, et al. Yeast, 2007 Jan. PMID 17192844
    2. Isolation and characterization of the Schizosaccharomyces pombe cDNA encoding the mitochondrial endonuclease(1). Ikeda S, et al. Biochim Biophys Acta, 2001 May 28. PMID 11406279
    3. Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization. Uemura T, et al. EMBO J, 1984 Aug. PMID 6090122, Free PMC Article
    4. Conserved strategies of RNA polymerase I hibernation and activation. Heiss FB, et al. Nat Commun, 2021 Feb 3. PMID 33536435, Free PMC Article
    5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA endonuclease activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA nuclease activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA nuclease activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded DNA endodeoxyribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA endodeoxyribonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial DNA catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitochondrial RNA catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase I EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    endodeoxyribonuclease Pnu1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4484695..4486032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020026.4 → NP_594598.2  endodeoxyribonuclease Pnu1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594598.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10480, Q9HFA0
      Conserved Domains (2) summary
      smart00477
      Location:78 → 289
      NUC; DNA/RNA non-specific endonuclease
      COG1864
      Location:5 → 309
      NUC1; DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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