Cct8l1 chaperonin containing TCP1 subunit 8-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cct8l1provided by MGI
Official Full Name: chaperonin containing TCP1 subunit 8-like 1provided by MGI
Primary source: MGI:MGI:2685289
See related: Ensembl:ENSMUSG00000038044 AllianceGenome:MGI:2685289
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm443
Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be part of chaperonin-containing T-complex. Orthologous to human CCT8L1P (chaperonin containing TCP1 subunit 8 like 1, pseudogene) and CCT8L2 (chaperonin containing TCP1 subunit 8 like 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human all
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Genomic context

Location:: 5 B1; 5 12.35 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (25721065..25723025)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (25516067..25518027)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of chaperonin-containing T-complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: T-complex protein 1 subunit theta-like 2

Names: chaperonin containing TCP1, subunit 8 (theta)-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198621.2 → NP_941023.1 T-complex protein 1 subunit theta-like 2

See identical proteins and their annotated locations for NP_941023.1

Status: VALIDATED

Source sequence(s)

AK133375, BC050797

Consensus CDS

CCDS19134.1

UniProtKB/TrEMBL

Q80YT3

Related

ENSMUSP00000044932.8, ENSMUST00000045016.9

Conserved Domains (2) summary

pfam00118
Location:52 → 532

Cpn60_TCP1; TCP-1/cpn60 chaperonin family

cl02777
Location:35 → 532

chaperonin_like; chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I ...