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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001317231.2 → NP_001304160.1 mitochondrial carrier homolog 2 isoform 1x
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the longer, C-terminally extended isoform (1x). As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in the longer isoform is denoted by an 'X'.
- Source sequence(s)
-
AC104942, AK313032, AY380792
- UniProtKB/TrEMBL
-
Q53G34
- Conserved Domains (1) summary
-
- pfam00153
Location:128 → 192
- Mito_carr; Mitochondrial carrier protein
-
NM_001317232.2 → NP_001304161.1 mitochondrial carrier homolog 2 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame coding exon in the 5' region compared to variant 1. The resulting isoform (2) is shorter, missing an internal protein segment compared to isoform 1.
- Source sequence(s)
-
AC104942, AK313032, AY380792, BQ960010
- UniProtKB/TrEMBL
- E9PIE4, Q53G34
- Related
- ENSP00000432043.2, ENST00000530428.2
- Conserved Domains (1) summary
-
- pfam00153
Location:119 → 183
- Mito_carr; Mitochondrial carrier protein
-
NM_001317233.2 → NP_001304162.1 mitochondrial carrier homolog 2 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon in the 5' region, which results in translation initiation from an in-frame, downstream start codon compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1.
- Source sequence(s)
-
AC104942, AK295218, AK313032, AY380792
- UniProtKB/TrEMBL
-
B4DHQ0
- Conserved Domains (1) summary
-
- pfam00153
Location:1 → 44
- Mito_carr; Mitochondrial carrier protein
-
NM_014342.4 → NP_055157.1 mitochondrial carrier homolog 2 isoform 1
See identical proteins and their annotated locations for NP_055157.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the shorter isoform (1).
- Source sequence(s)
-
AC104942, AK313032, AY380792
- Consensus CDS
-
CCDS7943.1
- UniProtKB/Swiss-Prot
- B2R7L8, Q9Y6C9
- UniProtKB/TrEMBL
-
Q53G34
- Related
- ENSP00000303222.3, ENST00000302503.8
- Conserved Domains (1) summary
-
- pfam00153
Location:128 → 192
- Mito_carr; Mitochondrial carrier protein