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    him-19 FBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190809, updated on 9-Dec-2024

    Summary

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    Official Symbol
    him-19
    Official Full Name
    FBD domain-containing protein
    Primary source
    WormBase:WBGene00022390
    Locus tag
    CELE_Y95B8A.11
    See related
    AllianceGenome:WB:WBGene00022390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in meiotic DNA double-strand break formation and regulation of synaptonemal complex assembly. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See him-19 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (889767..895099, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA Neighboring gene DZF domain-containing protein Neighboring gene Phosphodiesterase;putative 3',5'-cyclic phosphodiesterase pde-6 Neighboring gene Bursicon;Bursicon subunit alpha;Secreted protein Neighboring gene Guanine nucleotide-binding protein alpha-16 subunit Neighboring gene ncRNA Neighboring gene Protein EMP46

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localization of HIM-19 in the C. elegans germline. Roelens B, et al. MicroPubl Biol, 2022. PMID 36035776, Free PMC Article
    2. Mutations in Caenorhabditis elegans him-19 show meiotic defects that worsen with age. Tang L, et al. Mol Biol Cell, 2010 Mar 15. PMID 20071466, Free PMC Article
    3. Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans. Baudrimont A, et al. PLoS Genet, 2010 Nov 24. PMID 21124819, Free PMC Article
    4. Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry. Baudrimont A, et al. Sci Adv, 2022 Feb 18. PMID 35171669, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in meiotic DNA double-strand break formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of synaptonemal complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FBD domain-containing protein
    NP_001293191.1
    • Confirmed by transcript evidence
    NP_001293192.1
    • Confirmed by transcript evidence
    NP_490789.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      889767..895099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306262.2 → NP_001293191.1  FBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293191.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CK14

    2. NM_058388.5 → NP_490789.3  FBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490789.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N2V7

    3. NM_001306263.3 → NP_001293192.1  FBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293192.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLF9
    Nucleotide Protein
    Heading Accession and Version

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