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    npr-31 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188235, updated on 9-Dec-2024

    Summary

    Official Symbol
    npr-31
    Official Full Name
    G-protein coupled receptors family 1 profile domain-containing protein
    Primary source
    WormBase:WBGene00020319
    Locus tag
    CELE_T07F8.2
    See related
    AllianceGenome:WB:WBGene00020319
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in neurons. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including GPR50 (G protein-coupled receptor 50); APLNR (apelin receptor); and MTNR1A (melatonin receptor 1A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See npr-31 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (7144607..7147383)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ELM2 domain-containing protein Neighboring gene Defective in germ line development protein 3 Neighboring gene Zinc finger PHD-type domain-containing protein Neighboring gene RNA-binding protein FUS

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptors family 1 profile domain-containing protein
    NP_495481.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7144607..7147383
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063080.3NP_495481.2  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495481.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91439
      Conserved Domains (1) summary
      cd00637
      Location:9306
      7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily