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    aakg-4 CBS domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187928, updated on 9-Dec-2024

    Summary

    Official Symbol
    aakg-4
    Official Full Name
    CBS domain-containing protein
    Primary source
    WormBase:WBGene00020135
    Locus tag
    CELE_T01B6.3
    See related
    AllianceGenome:WB:WBGene00020135
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in cellular response to glucose starvation; regulation of carbohydrate metabolic process; and regulation of carbon utilization. Predicted to be part of nucleotide-activated protein kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including accessory cell; dorsal nerve cord; neurons; non-striated muscle; and rectal epithelium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See aakg-4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (2314894..2319338, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Sulfhydryl oxidase Neighboring gene ncRNA Neighboring gene Unconventional myosin heavy chain 6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables AMP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to glucose starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of gluconeogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of carbon utilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of glycolytic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nucleotide-activated protein kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CBS domain-containing protein
    NP_741725.2
    • Confirmed by transcript evidence
    NP_741726.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2314894..2319338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171633.7NP_741726.2  CBS domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741726.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MPT4
      Conserved Domains (1) summary
      cd02205
      Location:6120
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
    2. NM_171632.4NP_741725.2  CBS domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741725.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0K0
      Conserved Domains (3) summary
      COG0517
      Location:318436
      CBS; CBS domain [Signal transduction mechanisms]
      cd02205
      Location:319438
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
      cd04618
      Location:163288
      CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...