rbc-1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: rbc-1
Official Full Name: RAVE complex protein Rav1 C-terminal domain-containing protein
Primary source: WormBase:WBGene00004313
Locus tag: CELE_F54E4.1
See related: AllianceGenome:WB:WBGene00004313
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in vacuolar acidification. Predicted to be part of RAVE complex. Is expressed in several structures, including cuticle; neurons; ventral nerve cord; vm1; and vulva. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 71 and developmental and epileptic encephalopathy 81. Orthologous to human DMXL1 (Dmx like 1) and DMXL2 (Dmx like 2). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See rbc-1 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 33

Sequence:: Chromosome: X; NC_003284.9 (14611374..14624863)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

F54E4.1 (e-PCR)
- UniSTS:311786

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in vacuolar acidification	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of RAVE complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: RAVE complex protein Rav1 C-terminal domain-containing protein

NP_001360775.1

Confirmed by transcript evidence

NP_001368146.1

Confirmed by transcript evidence

NP_001368756.1

Confirmed by transcript evidence

NP_001368757.1

Confirmed by transcript evidence

NP_001368758.1

Confirmed by transcript evidence

NP_001368759.1

Confirmed by transcript evidence

NP_001368760.1

Confirmed by transcript evidence

NP_001379518.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

14611374..14624863

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001381156.2 → NP_001368760.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0IL12

Conserved Domains (3) summary

sd00039
Location:2784 → 2822

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1113 → 1847

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2728 → 3003

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001373583.1 → NP_001360775.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0INT8

Conserved Domains (3) summary

sd00039
Location:2769 → 2807

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1113 → 1847

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2704 → 2988

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001392889.1 → NP_001379518.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D6R8W9

Conserved Domains (3) summary

sd00039
Location:2780 → 2818

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1124 → 1858

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2715 → 2999

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001381155.1 → NP_001368146.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

J7S122

Conserved Domains (3) summary

sd00039
Location:2795 → 2833

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1124 → 1858

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2739 → 3014

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001381151.1 → NP_001368758.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0IKJ4

Conserved Domains (3) summary

sd00039
Location:2797 → 2835

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1126 → 1860

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2741 → 3016

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001381152.1 → NP_001368759.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0IKG1

Conserved Domains (3) summary

sd00039
Location:2782 → 2820

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1126 → 1860

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2717 → 3001

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001381153.1 → NP_001368756.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0ILV9

Conserved Domains (3) summary

sd00039
Location:2786 → 2824

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1115 → 1849

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2730 → 3005

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001381154.1 → NP_001368757.1 RAVE complex protein Rav1 C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0IM91

Conserved Domains (3) summary

sd00039
Location:2771 → 2809

7WD40; WD40 repeat [structural motif]

pfam12234
Location:1115 → 1849

Rav1p_C; RAVE protein 1 C terminal

cl29593
Location:2706 → 2990

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...