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    vit-5 Vitellogenin-5 [ Caenorhabditis elegans ]

    Gene ID: 180630, updated on 9-Dec-2024

    Summary

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    Official Symbol
    vit-5
    Official Full Name
    Vitellogenin-5
    Primary source
    WormBase:WBGene00006929
    Locus tag
    CELE_C04F6.1
    See related
    AllianceGenome:WB:WBGene00006929
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See vit-5 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (3403471..3408603)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene putative endochitinase Neighboring gene Gag-pol polyprotein Neighboring gene Actin-interacting protein 1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Production of YP170 Vitellogenins Promotes Intestinal Senescence in Caenorhabditis elegans. Sornda T, et al. J Gerontol A Biol Sci Med Sci, 2019 Jul 12. PMID 30854561, Free PMC Article
    2. Comparison of a vitellogenin gene between two distantly related rhabditid nematode species. Winter CE, et al. Mol Biol Evol, 1996 May. PMID 8676742
    3. Alternatively spliced transcripts of the flp-1 gene encode distinct FMRFamide-like peptides in Caenorhabditis elegans. Rosoff ML, et al. J Neurosci, 1992 Jun. PMID 1607945, Free PMC Article
    4. Regulation of lipoprotein assembly, secretion and fatty acid β-oxidation by Krüppel-like transcription factor, klf-3. Zhang J, et al. J Mol Biol, 2013 Aug 9. PMID 23639358, Free PMC Article
    5. Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans. Harvald EB, et al. Cell Syst, 2017 Jul 26. PMID 28734827

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nutrient reservoir activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vitellogenin-5
    NP_508589.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3403471..3408603
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076188.7 → NP_508589.1  Vitellogenin-5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508589.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P06125
      Conserved Domains (3) summary
      smart00216
      Location:1300 → 1454
      VWD; von Willebrand factor (vWF) type D domain
      pfam01347
      Location:24 → 617
      Vitellogenin_N; Lipoprotein amino terminal region
      pfam09172
      Location:651 → 942
      DUF1943; Domain of unknown function (DUF1943)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P06125.2

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