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    cpt-5 Choline/carnitine acyltransferase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179881, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cpt-5
    Official Full Name
    Choline/carnitine acyltransferase domain-containing protein
    Primary source
    WormBase:WBGene00008629
    Locus tag
    CELE_F09F3.9
    See related
    AllianceGenome:WB:WBGene00008629
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cpt-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (13873195..13875888)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene GP-PDE domain-containing protein Neighboring gene Fatty acid-binding protein homolog 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans. Taubert S, et al. Genes Dev, 2006 May 1. PMID 16651656, Free PMC Article
    2. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
    3. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
    4. Evolutionary analysis of the carnitine- and choline acyltransferases suggests distinct evolution of CPT2 versus CPT1 and related variants. van der Hoek MD, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2018 Aug. PMID 29730527
    5. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Brock TJ, et al. Genetics, 2007 Jun. PMID 17435249, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carnitine O-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carnitine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Choline/carnitine acyltransferase domain-containing protein
    NP_741637.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13873195..13875888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171549.6 → NP_741637.1  Choline/carnitine acyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741637.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EG54
      Conserved Domains (1) summary
      pfam00755
      Location:141 → 729
      Carn_acyltransf; Choline/Carnitine o-acyltransferase
    Nucleotide Protein
    Heading Accession and Version

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