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    abcf-1 ABC transporter domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abcf-1
    Official Full Name
    ABC transporter domain-containing protein
    Primary source
    WormBase:WBGene00006512
    Locus tag
    CELE_F18E2.2
    See related
    AllianceGenome:WB:WBGene00006512
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity. Is expressed in intestine; pharynx; and spermatheca. Orthologous to human ABCF1 (ATP binding cassette subfamily F member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abcf-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (12761044..12763375, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Purple acid phosphatase Neighboring gene Uncharacterized protein Neighboring gene Cohesin subunit scc-3 Neighboring gene Serpentine Receptor, class T Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP-binding cassette transporters are required for efficient RNA interference in Caenorhabditis elegans. Sundaram P, et al. Mol Biol Cell, 2006 Aug. PMID 16723499, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ABC transporter domain-containing protein
    NP_506192.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12761044..12763375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073791.6 → NP_506192.1  ABC transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506192.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19554
      Conserved Domains (3) summary
      cd03221
      Location:407 → 595
      ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
      COG0488
      Location:77 → 609
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      pfam12848
      Location:295 → 353
      ABC_tran_Xtn; ABC transporter
    Nucleotide Protein
    Heading Accession and Version

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