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    his-46 Histone H4 [ Caenorhabditis elegans ]

    Gene ID: 178050, updated on 9-Dec-2024

    Summary

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    Official Symbol
    his-46
    Official Full Name
    Histone H4
    Primary source
    WormBase:WBGene00001920
    Locus tag
    CELE_B0035.9
    See related
    AllianceGenome:WB:WBGene00001920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Orthologous to several human genes including H4C1 (H4 clustered histone 1); H4C11 (H4 clustered histone 11); and H4C12 (H4 clustered histone 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See his-46 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (11326018..11326329, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H2A Neighboring gene putative histone H2B 4 Neighboring gene Histone H3 Neighboring gene Kinesin motor domain-containing protein Neighboring gene RNA polymerase-associated protein LEO1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article
    2. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
    3. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Histone H4
    NP_502133.1
    • Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11326018..11326329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069732.1 → NP_502133.1  Histone H4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502133.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02619, P02306, P18678, P62784, Q7JNV2
      Conserved Domains (1) summary
      PLN00035
      Location:1 → 103
      PLN00035; histone H4; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62784.2

    Gene LinkOut

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