F13B12.1 IWS1-like protein [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: F13B12.1
Official Full Name: IWS1-like protein
Primary source: WormBase:WBGene00008729
Locus tag: CELE_F13B12.1
See related: AllianceGenome:WB:WBGene00008729
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in poly(A)+ mRNA export from nucleus. Located in nucleus. Is expressed in several structures, including excretory cell; intestine; nervous system; non-striated muscle; and pharyngeal-intestinal valve. Orthologous to human IWS1 (interacts with SUPT6H, CTD assembly factor 1). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See F13B12.1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 4

Sequence:: Chromosome: IV; NC_003282.8 (10422610..10424635, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

F13B12.1 (e-PCR)
- UniSTS:321359

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in poly(A)+ mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: IWS1-like protein

NP_501924.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

10422610..10424635 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069523.8 → NP_501924.1 IWS1-like protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501924.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q19375

Conserved Domains (1) summary

cl00146
Location:237 → 418

TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme