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    ugt-45 glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 177139, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-45
    Official Full Name
    glucuronosyltransferase
    Primary source
    WormBase:WBGene00021372
    Locus tag
    CELE_Y37E11AR.5
    See related
    AllianceGenome:WB:WBGene00021372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-45 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (3748210..3751101, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase siah-1 Neighboring gene ncRNA Neighboring gene Ig-like domain-containing protein Neighboring gene Bestrophin homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aryl Hydrocarbon Receptor-Dependent and -Independent Pathways Mediate Curcumin Anti-Aging Effects. Brinkmann V, et al. Antioxidants (Basel), 2022 Mar 23. PMID 35453298, Free PMC Article
    2. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronosyltransferase
    NP_001294295.1
    • Confirmed by transcript evidence
    NP_500410.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3748210..3751101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068009.7 → NP_500410.2  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500410.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q965X5
      Conserved Domains (2) summary
      PHA03392
      Location:14 → 513
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:19 → 510
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. NM_001307366.3 → NP_001294295.1  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294295.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PLL6
      Conserved Domains (2) summary
      PHA03392
      Location:11 → 482
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:9 → 479
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version

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