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    appg-1 Activated in Blocked Unfolded protein response;Cysteine rich repeat-containing domain protein [ Caenorhabditis elegans ]

    Gene ID: 174597, updated on 9-Dec-2024

    Summary

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    Official Symbol
    appg-1
    Official Full Name
    Activated in Blocked Unfolded protein response;Cysteine rich repeat-containing domain protein
    Primary source
    WormBase:WBGene00010830
    Locus tag
    CELE_M02G9.1
    See related
    AllianceGenome:WB:WBGene00010830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in nervous system and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See appg-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (10326041..10335807)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Intrinsically Disordered Protein, expressed in Pharynx Neighboring gene ncRNA Neighboring gene Nucleolar complex protein 2 homolog Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
    2. A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, et al. Elife, 2022 Oct 19. PMID 36259463, Free PMC Article
    3. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    4. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response;Cysteine rich repeat-containing domain protein
    NP_001254244.1
    • Partially confirmed by transcript evidence
    NP_001254245.1
    • Confirmed by transcript evidence
    NP_001391115.1
    • Confirmed by transcript evidence
    NP_001391116.1
    • Confirmed by transcript evidence
    NP_001391117.1
    • Confirmed by transcript evidence
    NP_001391118.1
    • Partially confirmed by transcript evidence
    NP_001408258.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10326041..10335807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267316.2 → NP_001254245.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254245.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O17970
      Conserved Domains (1) summary
      PRK10263
      Location:568 → 778
      PRK10263; DNA translocase FtsK; Provisional

    2. NM_001267315.4 → NP_001254244.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254244.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6VQ93
      Conserved Domains (1) summary
      PRK10263
      Location:670 → 805
      PRK10263; DNA translocase FtsK; Provisional

    3. NM_001404233.1 → NP_001391115.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QAW1

    4. NM_001404234.1 → NP_001391116.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QF54

    5. NM_001404232.1 → NP_001391117.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QD18

    6. NM_001404235.1 → NP_001391118.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QBS1

    7. NM_001421350.1 → NP_001408258.1  Cysteine rich repeat-containing domain protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QB22
    Nucleotide Protein
    Heading Accession and Version

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