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    taf-11.2 TAFII28-like protein domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172451, updated on 2-Nov-2024

    Summary

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    Official Symbol
    taf-11.2
    Official Full Name
    TAFII28-like protein domain-containing protein
    Primary source
    WormBase:WBGene00006394
    Locus tag
    CELE_K10D3.3
    See related
    AllianceGenome:WB:WBGene00006394
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to several human genes including TAF11 (TATA-box binding protein associated factor 11); TAF11L10 (TATA-box binding protein associated factor 11 like 10); and TAF11L11 (TATA-box binding protein associated factor 11 like 11). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See taf-11.2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (7132747..7134370)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene RUN domain-containing protein Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein Neighboring gene FErroChelatase-Like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Metazoan operons accelerate recovery from growth-arrested states. Zaslaver A, et al. Cell, 2011 Jun 10. PMID 21663799, Free PMC Article
    2. Distinct requirements for C.elegans TAF(II)s in early embryonic transcription. Walker AK, et al. EMBO J, 2001 Sep 17. PMID 11566890, Free PMC Article
    3. Transcription mechanisms. Blackwell TK, et al. WormBook, 2006 Sep 5. PMID 18050436, Free PMC Article
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TAFII28-like protein domain-containing protein
    NP_492019.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7132747..7134370
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059618.6 → NP_492019.2  TAFII28-like protein domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21417
      Conserved Domains (1) summary
      cd08048
      Location:182 → 267
      TAF11; TATA Binding Protein (TBP) Associated Factor 11 (TAF11) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
    Nucleotide Protein
    Heading Accession and Version

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