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    trpp-8 Trafficking protein particle complex subunit 8 [ Caenorhabditis elegans ]

    Gene ID: 172217, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trpp-8
    Official Full Name
    Trafficking protein particle complex subunit 8
    Primary source
    WormBase:WBGene00018512
    Locus tag
    CELE_F46F11.9
    See related
    AllianceGenome:WB:WBGene00018512
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be part of TRAPPIII protein complex. Orthologous to human TRAPPC8 (trafficking protein particle complex subunit 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trpp-8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (5610374..5616402, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like protein 5 Neighboring gene putative V-type proton ATPase subunit G Neighboring gene ncRNA Neighboring gene F-box domain-containing protein Neighboring gene CSD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites. Aguirre-Chen C, et al. Development, 2011 Feb. PMID 21205795, Free PMC Article
    2. Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. Zhang Z, et al. Sci Adv, 2020 Feb. PMID 32095531, Free PMC Article
    3. The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response. Zhang Z, et al. PLoS Genet, 2021 Feb. PMID 33524011, Free PMC Article
    4. Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Schmitz C, et al. Proc Natl Acad Sci U S A, 2007 Jan 16. PMID 17213328, Free PMC Article
    5. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of TRAPPIII protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Trafficking protein particle complex subunit 8
    NP_491642.2
    • Confirmed by transcript evidence
    NP_491643.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5610374..5616402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059242.6 → NP_491643.2  Trafficking protein particle complex subunit 8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491643.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L043
      Conserved Domains (1) summary
      pfam12739
      Location:128 → 556
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit

    2. NM_059241.7 → NP_491642.2  Trafficking protein particle complex subunit 8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491642.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9BI63
      Conserved Domains (1) summary
      pfam12739
      Location:128 → 558
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit
    Nucleotide Protein
    Heading Accession and Version

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