Ebf3 early B cell factor 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ebf3provided by MGI
Official Full Name: early B cell factor 3provided by MGI
Primary source: MGI:MGI:894289
See related: Ensembl:ENSMUSG00000010476 AllianceGenome:MGI:894289
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: O/E-2; mKIAA4201; 3110018A08Rik
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Orthologous to human EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in CNS E14 (RPKM 24.6), limb E14.5 (RPKM 23.6) and 9 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F3- F4; 7 82.26 cM

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (136795400..136924528, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (137193671..137322805, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Early B Cell Factor 3 (EBF3) attenuates Parkinson's disease through directly regulating contactin-associated protein-like 4 (CNTNAP4) transcription: An experimental study.
Title: Early B Cell Factor 3 (EBF3) attenuates Parkinson's disease through directly regulating contactin-associated protein-like 4 (CNTNAP4) transcription: An experimental study.
Ebf3[+] niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells.
Title: Ebf3(+) niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells.
The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.
Title: The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.
HSC cellular niches express Ebf3 that is required to create HSC niches, to inhibit their osteoblast differentiation, and to maintain spaces for HSCs.
Title: Stem cell niche-specific Ebf3 maintains the bone marrow cavity.
data show that Prdm13 is not required for amacrine fate as a class, but is essential for the formation of Ebf3+ amacrine cell subtypes. Rather than driving subtype identity, Prdm13 may act by restricting competing fate programs to maintain identity and survival.
Title: Prdm13 is required for Ebf3+ amacrine cell formation in the retina.
Our findings highlight the critical role of Ebf3 in multipolar-to-bipolar transition via positive feedback regulation of NeuroD1 in the developing neocortex.
Title: A Prdm8 target gene Ebf3 regulates multipolar-to-bipolar transition in migrating neocortical cells.
Ebf3 is a new regulator of terminal muscle differentiation in the diaphragm, and Ebf factors cooperate with MyoD in the induction of muscle-specific genes
Title: Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.
The regulation of Ebf3 expression by miR218 controls the terminal differentiation of dopaminergic neurons.
Title: Ebf3-miR218 regulation is involved in the development of dopaminergic neurons.
Ebf2 and Ebf3, singly or together, control the migration of Cajal-Retzius cells arising in the cortical hem. These findings provide evidence that Ebfs directly regulate Cajal-Retzius cell development
Title: Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (6)
Targeted (6) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:235798

D14S292 (e-PCR), detects polymorphism
- UniSTS:39460

RH124501 (e-PCR)
- UniSTS:161323

AW742548 (e-PCR)
- UniSTS:208222

Ebf3 (e-PCR), detects polymorphism
- UniSTS:545928

PMC134715P4 (e-PCR)
- UniSTS:270746

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: transcription factor COE3

Names: EBF-3; OE-2; Olf-1/EBF-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113414.2 → NP_001106885.1 transcription factor COE3 isoform 2

See identical proteins and their annotated locations for NP_001106885.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternative, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a shorter isoform (2) that is missing a 9 aa segment, compared to isoform 1.

Source sequence(s)

AC135639

Consensus CDS

CCDS52423.1

UniProtKB/TrEMBL

Q6NXL3, Q8CBL7

Related

ENSMUSP00000132563.3, ENSMUST00000169486.9

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
NM_001113415.2 → NP_001106886.1 transcription factor COE3 isoform 1

See identical proteins and their annotated locations for NP_001106886.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes the longest isoform (1)

Source sequence(s)

AC135639

Consensus CDS

CCDS52422.1

UniProtKB/Swiss-Prot

O08791, O08793

UniProtKB/TrEMBL

Q8CBL7

Related

ENSMUSP00000147829.2, ENSMUST00000210774.2

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
NM_010096.4 → NP_034226.1 transcription factor COE3 isoform 3

See identical proteins and their annotated locations for NP_034226.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) uses an alternate, in-frame donor acceptor site at the penultimate coding exon, and an alternative, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a shorter isoform (3) that is missing 36 aa and 9 aa segments, compared to isoform 1.

Source sequence(s)

AC135639

Consensus CDS

CCDS21946.1

UniProtKB/TrEMBL

Q5DTH8

Related

ENSMUSP00000033378.6, ENSMUST00000033378.13

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

136795400..136924528 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036152643.1 → XP_036008536.1 transcription factor COE3 isoform X1

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152647.1 → XP_036008540.1 transcription factor COE3 isoform X3

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152646.1 → XP_036008539.1 transcription factor COE3 isoform X3

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152645.1 → XP_036008538.1 transcription factor COE3 isoform X1

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152644.1 → XP_036008537.1 transcription factor COE3 isoform X1

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507334.3 → XP_006507397.1 transcription factor COE3 isoform X10

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507336.3 → XP_006507399.1 transcription factor COE3 isoform X14

See identical proteins and their annotated locations for XP_006507399.1

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507331.3 → XP_006507394.1 transcription factor COE3 isoform X2

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242085.2 → XP_030097945.1 transcription factor COE3 isoform X1

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242086.2 → XP_030097946.1 transcription factor COE3 isoform X4

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242094.2 → XP_030097954.1 transcription factor COE3 isoform X17

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain
XM_030242092.2 → XP_030097952.1 transcription factor COE3 isoform X13

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507333.3 → XP_006507396.1 transcription factor COE3 isoform X6

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242095.2 → XP_030097955.1 transcription factor COE3 isoform X18

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_011241672.3 → XP_011239974.1 transcription factor COE3 isoform X15

See identical proteins and their annotated locations for XP_011239974.1

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507332.3 → XP_006507395.1 transcription factor COE3 isoform X3

UniProtKB/TrEMBL

Q8CBL7

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242087.2 → XP_030097947.1 transcription factor COE3 isoform X5

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242088.2 → XP_030097948.1 transcription factor COE3 isoform X7

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242093.2 → XP_030097953.1 transcription factor COE3 isoform X16

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152651.1 → XP_036008544.1 transcription factor COE3 isoform X21

Conserved Domains (3) summary

cd01175
Location:47 → 131

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16423
Location:132 → 175

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

cl17007
Location:1 → 40

COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
XM_036152650.1 → XP_036008543.1 transcription factor COE3 isoform X20

Conserved Domains (3) summary

cd01175
Location:56 → 140

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16423
Location:141 → 184

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

cl17007
Location:1 → 40

COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
XM_036152652.1 → XP_036008545.1 transcription factor COE3 isoform X22

Conserved Domains (3) summary

cd01175
Location:47 → 131

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16423
Location:132 → 175

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

cl17007
Location:1 → 40

COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
XM_030242090.2 → XP_030097950.1 transcription factor COE3 isoform X9

UniProtKB/TrEMBL

Q6NXL3, Q8CBL7

Related

ENSMUSP00000101724.4, ENSMUST00000106118.10

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507335.3 → XP_006507398.1 transcription factor COE3 isoform X11

See identical proteins and their annotated locations for XP_006507398.1

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_036152653.1 → XP_036008546.1 transcription factor COE3 isoform X23

UniProtKB/TrEMBL

Q3UUB6

Related

ENSMUSP00000147512.2, ENSMUST00000209578.2

Conserved Domains (3) summary

cd01175
Location:47 → 131

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16423
Location:132 → 175

COE1_HLH; Transcription factor COE1 helix-loop-helix domain

cl17007
Location:1 → 40

COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
XM_030242091.2 → XP_030097951.1 transcription factor COE3 isoform X12

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_030242089.2 → XP_030097949.1 transcription factor COE3 isoform X8

UniProtKB/TrEMBL

Q5DTH8

Conserved Domains (3) summary

cd01175
Location:254 → 338

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:339 → 382

COE1_HLH; Transcription factor COE1 helix-loop-helix domain
XM_006507337.5 → XP_006507400.1 transcription factor COE3 isoform X19

Conserved Domains (3) summary

cd01175
Location:263 → 347

IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...

pfam16422
Location:21 → 247

COE1_DBD; Transcription factor COE1 DNA-binding domain

pfam16423
Location:348 → 391

COE1_HLH; Transcription factor COE1 helix-loop-helix domain