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    LOC128927781 CapStarr-seq enhancer MGSCv37_chr18:32069964-32070147 [ Mus musculus (house mouse) ]

    Gene ID: 128927781, updated on 8-Feb-2024

    Summary

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    Gene symbol
    LOC128927781
    Gene description
    CapStarr-seq enhancer MGSCv37_chr18:32069964-32070147
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rr370350
    Summary
    This genomic region was identified as a candidate cis-regulatory module (CRM) in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. It was validated as an active enhancer by high-throughput CapStarr-seq reporter assays showing weak activity in P5424 T cells and NIH3T3 fibroblasts. [provided by RefSeq, Mar 2023]
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    Genomic context

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    See LOC128927781 in Genome Data Viewer
    Location:
    chromosome: 18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (32043363..32043546)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3226 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide D Neighboring gene STARR-positive B cell enhancer mm9_chr18:31963552-31963852 Neighboring gene STARR-positive B cell enhancer ABC_E10983 Neighboring gene WD repeat domain 33 Neighboring gene glutathione S-transferase, mu 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_44149 Neighboring gene SFT2 domain containing 3 Neighboring gene STARR-seq mESC enhancer starr_44150 Neighboring gene LIM and senescent cell antigen like domains 2 Neighboring gene predicted gene, 46619 Neighboring gene G protein-coupled receptor 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq. Vanhille L, et al. Nat Commun, 2015 Apr 15. PMID 25872643

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • regulatory region 370350

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_153391.1 

      Range
      101..284
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      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      32043363..32043546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version