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    LOC127893607 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48064159-48064670 [ Homo sapiens (human) ]

    Gene ID: 127893607, updated on 12-Sep-2024

    Summary

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    Gene symbol
    LOC127893607
    Gene description
    H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48064159-48064670
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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    Genomic context

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    See LOC127893607 in Genome Data Viewer
    Location:
    chromosome: 20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (49447622..49448133)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (51217232..51217743)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (48064159..48064670)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904925 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:47934991-47935572 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:47935573-47936154 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:47940265-47940766 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:47940767-47941266 Neighboring gene uncharacterized LOC105372649 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18061 Neighboring gene NANOG hESC enhancer GRCh37_chr20:47985158-47985711 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:47990213-47990475 Neighboring gene potassium voltage-gated channel subfamily B member 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48040793-48041316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48041317-48041840 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48063649-48064158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48063137-48063648 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12997 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12998 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48121719-48122220 Neighboring gene prostaglandin I2 synthase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18062 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:48158843-48159119 Neighboring gene uncharacterized LOC101927486 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48184974-48185590 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48185591-48186205 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48196657-48197231 Neighboring gene uncharacterized LOC105372651 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48212298-48212798

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_143329.1 

      Range
      101..612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      49447622..49448133
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      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      51217232..51217743
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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