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    rgl3a ral guanine nucleotide dissociation stimulator-like 3a [ Thunnus albacares (yellowfin tuna) ]

    Gene ID: 122979072, updated on 22-Mar-2024

    Summary

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    Gene symbol
    rgl3a
    Gene description
    ral guanine nucleotide dissociation stimulator-like 3a
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Thunnus albacares
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Pelagiaria; Scombriformes; Scombridae; Thunnus
    Orthologs
    zebrafish all
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    Genomic context

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    See rgl3a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    100 current fThuAlb1.1 (GCF_914725855.1) 3 NC_058108.1 (9387141..9406666, complement)

    Chromosome 3 - NC_058108.1Genomic Context describing neighboring genes Neighboring gene nuclear factor, interleukin 3 regulated, member 3 Neighboring gene nuclear factor, interleukin 3 regulated, member 5 Neighboring gene uncharacterized LOC122979073 Neighboring gene outer dynein arm docking complex subunit 3 Neighboring gene solute carrier family 44 member 2 (CTL2 blood group)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_058108.1 Chromosome 3 Reference fThuAlb1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substitutions in the Glycogenin-1 Gene Are Associated with the Evolution of Endothermy in Sharks and Tunas. Ciezarek AG, et al. Genome Biol Evol, 2016 Oct 5. PMID 27614233, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ral guanine nucleotide dissociation stimulator-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Thunnus albacares Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fThuAlb1.1

    Genomic

    1. NC_058108.1 Reference fThuAlb1.1

      Range
      9387141..9406666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044346254.1 → XP_044202189.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      Conserved Domains (3) summary
      smart00147
      Location:268 → 569
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd00153
      Location:704 → 790
      RA_RalGDS_like; Ras-associating (RA) domain of RalGDS family
      cl02520
      Location:110 → 224
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

    2. XM_044346251.1 → XP_044202186.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      Conserved Domains (3) summary
      smart00147
      Location:268 → 569
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd00153
      Location:704 → 790
      RA_RalGDS_like; Ras-associating (RA) domain of RalGDS family
      cl02520
      Location:110 → 224
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

    3. XM_044346253.1 → XP_044202188.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      Conserved Domains (3) summary
      smart00147
      Location:268 → 569
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd00153
      Location:704 → 790
      RA_RalGDS_like; Ras-associating (RA) domain of RalGDS family
      cl02520
      Location:110 → 224
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

    4. XM_044346250.1 → XP_044202185.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      Conserved Domains (3) summary
      smart00147
      Location:268 → 569
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd00153
      Location:704 → 790
      RA_RalGDS_like; Ras-associating (RA) domain of RalGDS family
      cl02520
      Location:110 → 224
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

    5. XM_044346255.1 → XP_044202190.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X2

      Conserved Domains (3) summary
      smart00147
      Location:213 → 514
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd00153
      Location:649 → 735
      RA_RalGDS_like; Ras-associating (RA) domain of RalGDS family
      cl02520
      Location:55 → 169
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    Nucleotide Protein
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