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    IKBKB inhibitor of nuclear factor kappa B kinase subunit beta [ Cervus canadensis ]

    Gene ID: 122432633, updated on 22-Mar-2024

    Summary

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    Gene symbol
    IKBKB
    Gene description
    inhibitor of nuclear factor kappa B kinase subunit beta
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cervus canadensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae; Cervinae; Cervus
    Orthologs
    human mouse all
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    Genomic context

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    See IKBKB in Genome Data Viewer
    Location:
    chromosome: 31
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current ASM1932006v1 (GCF_019320065.1) 31 NC_057416.1 (34913452..34964080)

    Chromosome 31 - NC_057416.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene plasminogen activator, tissue type Neighboring gene uncharacterized LOC122432638 Neighboring gene ribosomal biogenesis factor-like Neighboring gene DNA polymerase beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_057416.1 Chromosome 31 Reference ASM1932006v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables IkappaB kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of IkappaB kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibitor of nuclear factor kappa-B kinase subunit beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cervus canadensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1932006v1

    Genomic

    1. NC_057416.1 Reference ASM1932006v1

      Range
      34913452..34964080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_043454697.1 → XP_043310632.1  inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2

      Conserved Domains (2) summary
      cd14038
      Location:20 → 309
      STKc_IKK_beta; Catalytic domain of the Serine/Threonine kinase, Inhibitor of Nuclear Factor-KappaB Kinase (IKK) beta
      cd17046
      Location:310 → 390
      Ubl_IKKA_like; ubiquitin-like (Ubl) domain found in inhibitor of nuclear factor kappa-B kinases, IKK-alpha and IKK-beta, and similar proteins

    2. XM_043454695.1 → XP_043310630.1  inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1

      Conserved Domains (2) summary
      cd14038
      Location:20 → 309
      STKc_IKK_beta; Catalytic domain of the Serine/Threonine kinase, Inhibitor of Nuclear Factor-KappaB Kinase (IKK) beta
      cd17046
      Location:310 → 390
      Ubl_IKKA_like; ubiquitin-like (Ubl) domain found in inhibitor of nuclear factor kappa-B kinases, IKK-alpha and IKK-beta, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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