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    KIT KIT proto-oncogene, receptor tyrosine kinase [ Lagopus leucura (white-tailed ptarmigan) ]

    Gene ID: 122180382, updated on 22-Mar-2024

    Summary

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    Gene symbol
    KIT
    Gene description
    KIT proto-oncogene, receptor tyrosine kinase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lagopus leucura
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Tetraoninae; Lagopus
    Orthologs
    human mouse all
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    Genomic context

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    See KIT in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    100 current USGS_WTPT01 (GCF_019238085.1) Unplaced Scaffold NW_024962264.1 (44734023..44785754, complement)

    NW_024962264.1Genomic Context describing neighboring genes Neighboring gene steroid 5 alpha-reductase 3 Neighboring gene kinase insert domain receptor Neighboring gene platelet derived growth factor receptor alpha Neighboring gene GS homeobox 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024962264 Unplaced Scaffold Reference USGS_WTPT01

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in B cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Fc receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Kit signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mast/stem cell growth factor receptor Kit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Lagopus leucura Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USGS_WTPT01

    Genomic

    1. NW_024962264.1 Reference USGS_WTPT01

      Range
      44734023..44785754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042871996.1 → XP_042727930.1  mast/stem cell growth factor receptor Kit

      Conserved Domains (3) summary
      smart00409
      Location:213 → 292
      IG; Immunoglobulin
      smart00410
      Location:31 → 101
      IG_like; Immunoglobulin like
      cd05104
      Location:539 → 913
      PTKc_Kit; Catalytic domain of the Protein Tyrosine Kinase, Kit
    Nucleotide Protein
    Heading Accession and Version

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