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    LOC121599732 ecdysone receptor [ Anopheles merus ]

    Gene ID: 121599732, updated on 19-Jun-2024

    Summary

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    Gene symbol
    LOC121599732
    Gene description
    ecdysone receptor
    See related
    VectorBase:AMEM21_005583
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles merus
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Orthologs
    fruit fly all
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    Genomic context

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    See LOC121599732 in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    100 current AmerM5.1 (GCF_017562075.2) 3L NC_054085.1 (36709097..36895601)

    Chromosome 3L - NC_054085.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein C16orf52 homolog A Neighboring gene glycosyltransferase 25 family member Neighboring gene uncharacterized LOC121599734 Neighboring gene uncharacterized LOC121599648

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_054085.1 Chromosome 3L Reference AmerM5.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ecdysone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ecdysone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ecdysone receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Anopheles merus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference AmerM5.1 Primary Assembly

    Genomic

    1. NC_054085.1 Reference AmerM5.1 Primary Assembly

      Range
      36709097..36895601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041927772.1 → XP_041783706.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    2. XM_041927771.1 → XP_041783705.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    3. XM_041927770.1 → XP_041783704.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    4. XM_041927773.1 → XP_041783707.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    5. XM_041927769.1 → XP_041783703.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    6. XM_041927774.1 → XP_041783708.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    7. XM_041927775.1 → XP_041783709.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:483 → 716
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:329 → 419
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      COG5422
      Location:227 → 320
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      pfam07482
      Location:105 → 167
      DUF1522; Domain of Unknown Function (DUF1522)

    8. XM_041927780.1 → XP_041783714.1  ecdysone receptor isoform X2

      UniProtKB/TrEMBL
      A0A182VPJ8
      Conserved Domains (2) summary
      cd06938
      Location:360 → 593
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers

    9. XM_041927776.1 → XP_041783710.1  ecdysone receptor isoform X2

      UniProtKB/TrEMBL
      A0A182VPJ8
      Conserved Domains (2) summary
      cd06938
      Location:360 → 593
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers

    10. XM_041927779.1 → XP_041783713.1  ecdysone receptor isoform X2

      UniProtKB/TrEMBL
      A0A182VPJ8
      Conserved Domains (2) summary
      cd06938
      Location:360 → 593
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers

    11. XM_041927777.1 → XP_041783711.1  ecdysone receptor isoform X2

      UniProtKB/TrEMBL
      A0A182VPJ8
      Conserved Domains (2) summary
      cd06938
      Location:360 → 593
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers

    12. XM_041927781.1 → XP_041783715.1  ecdysone receptor isoform X2

      UniProtKB/TrEMBL
      A0A182VPJ8
      Conserved Domains (2) summary
      cd06938
      Location:360 → 593
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
    Nucleotide Protein Strain
    Heading Accession and Version

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