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    TRAF2 TNF receptor associated factor 2 [ Cygnus olor (mute swan) ]

    Gene ID: 121057583, updated on 22-Mar-2024

    Summary

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    Gene symbol
    TRAF2
    Gene description
    TNF receptor associated factor 2
    See related
    EnsemblRapid:ENSCOLG00015003567
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cygnus olor
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Cygnus
    Orthologs
    human mouse all
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    Genomic context

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    See TRAF2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    100 current bCygOlo1.pri.v2 (GCF_009769625.2) 19 NC_049187.1 (423929..447609, complement)

    Chromosome 19 - NC_049187.1Genomic Context describing neighboring genes Neighboring gene complement C8 gamma chain Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene endothelial differentiation related factor 1 Neighboring gene MAM domain containing 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_049187.1 Chromosome 19 Reference bCygOlo1.pri.v2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of plasma membrane signaling receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TNF receptor-associated factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cygnus olor Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bCygOlo1.pri.v2 Primary Assembly

    Genomic

    1. NC_049187.1 Reference bCygOlo1.pri.v2 Primary Assembly

      Range
      423929..447609 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040531976.1 → XP_040387910.1  TNF receptor-associated factor 2 isoform X1

      Related
      ENSCOLP00015005775.1, ENSCOLT00015006281.1
      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 529
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    2. XM_040531977.1 → XP_040387911.1  TNF receptor-associated factor 2 isoform X1

      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 529
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    3. XM_040531984.1 → XP_040387918.1  TNF receptor-associated factor 2 isoform X3

      Conserved Domains (4) summary
      TIGR02169
      Location:206 → 300
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:287 → 450
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl40617
      Location:103 → 156
      zf-TRAF; TRAF-type zinc finger

    4. XM_040531981.1 → XP_040387915.1  TNF receptor-associated factor 2 isoform X2

      Conserved Domains (4) summary
      pfam02176
      Location:124 → 181
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:312 → 475
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:247 → 307
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    5. XM_040531980.1 → XP_040387914.1  TNF receptor-associated factor 2 isoform X2

      Conserved Domains (4) summary
      pfam02176
      Location:124 → 181
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:312 → 475
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:247 → 307
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    6. XM_040531975.1 → XP_040387909.1  TNF receptor-associated factor 2 isoform X1

      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 529
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    7. XM_040531982.1 → XP_040387916.1  TNF receptor-associated factor 2 isoform X2

      Conserved Domains (4) summary
      pfam02176
      Location:124 → 181
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:312 → 475
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:247 → 307
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    8. XM_040531983.1 → XP_040387917.1  TNF receptor-associated factor 2 isoform X2

      Related
      ENSCOLP00015005772.1, ENSCOLT00015006277.1
      Conserved Domains (4) summary
      pfam02176
      Location:124 → 181
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:312 → 475
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:247 → 307
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    9. XM_040531978.1 → XP_040387912.1  TNF receptor-associated factor 2 isoform X1

      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 529
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    10. XM_040531986.1 → XP_040387920.1  TNF receptor-associated factor 2 isoform X4

      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 411
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

    11. XM_040531987.1 → XP_040387921.1  TNF receptor-associated factor 2 isoform X4

      Conserved Domains (4) summary
      pfam02176
      Location:178 → 235
      zf-TRAF; TRAF-type zinc finger
      cd16639
      Location:32 → 73
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
      cl02446
      Location:366 → 411
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:301 → 361
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    Nucleotide Protein
    Heading Accession and Version

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