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    XRCC5 X-ray repair cross complementing 5 [ Mauremys reevesii (Reeves's turtle) ]

    Gene ID: 120374836, updated on 21-Mar-2024

    Summary

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    Gene symbol
    XRCC5
    Gene description
    X-ray repair cross complementing 5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mauremys reevesii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
    Orthologs
    human mouse all
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    Genomic context

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    See XRCC5 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    22
    Annotation release Status Assembly LG Location
    100 current ASM1616193v1 (GCF_016161935.1) 11 NC_052633.1 (72450304..72534791)

    Linkage Group 11 - NC_052633.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD36 Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene transmembrane protein 169 Neighboring gene membrane associated ring-CH-type finger 4 Neighboring gene SNF2 related chromatin remodeling annealing helicase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_052633.1 Chromosome 11 Reference ASM1616193v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to X-ray IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to gamma radiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ku70:Ku80 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    X-ray repair cross-complementing protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mauremys reevesii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1616193v1 Primary Assembly

    Genomic

    1. NC_052633.1 Reference ASM1616193v1 Primary Assembly

      Range
      72450304..72534791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039495162.1 → XP_039351096.1  X-ray repair cross-complementing protein 5 isoform X1

      Conserved Domains (3) summary
      cd00873
      Location:243 → 541
      KU80; Ku-core domain, Ku80 subfamily; Ku80 is a subunit of the Ku protein, which plays a key role in multiple nuclear processes such as DNA repair, chromosome maintenance, transcription regulation, and V(D)J recombination. The mechanism underlying the ...
      pfam03731
      Location:9 → 243
      Ku_N; Ku70/Ku80 N-terminal alpha/beta domain
      pfam08785
      Location:593 → 705
      Ku_PK_bind; Ku C terminal domain like

    2. XM_039495163.1 → XP_039351097.1  X-ray repair cross-complementing protein 5 isoform X2

      Conserved Domains (3) summary
      cd00873
      Location:230 → 528
      KU80; Ku-core domain, Ku80 subfamily; Ku80 is a subunit of the Ku protein, which plays a key role in multiple nuclear processes such as DNA repair, chromosome maintenance, transcription regulation, and V(D)J recombination. The mechanism underlying the ...
      pfam03731
      Location:1 → 230
      Ku_N; Ku70/Ku80 N-terminal alpha/beta domain
      pfam08785
      Location:580 → 692
      Ku_PK_bind; Ku C terminal domain like
    Nucleotide Protein
    Heading Accession and Version

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