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    TH tyrosine hydroxylase [ Molothrus ater ]

    Gene ID: 118687311, updated on 3-Aug-2024

    Summary

    Gene symbol
    TH
    Gene description
    tyrosine hydroxylase
    See related
    EnsemblRapid:ENSMRTG00000014331
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Molothrus ater
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Icteridae; Molothrus
    Orthologs
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    Genomic context

    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_03 current BPBGC_Mater_1.1 (GCF_012460135.2) 6 NC_050483.2 (15773745..15796516)
    100 previous assembly BPBGC_Mater_1.0 (GCF_012460135.1) 5 NC_050482.1 (15656190..15672586)

    Chromosome 6 - NC_050483.2Genomic Context describing neighboring genes Neighboring gene tetraspanin 32 Neighboring gene achaete-scute family bHLH transcription factor 2 Neighboring gene insulin Neighboring gene insulin like growth factor 2

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables tyrosine 3-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in dopamine biosynthetic process from tyrosine IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_012460135.2-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference BPBGC_Mater_1.1 Primary Assembly

    Genomic

    1. NC_050483.2 Reference BPBGC_Mater_1.1 Primary Assembly

      Range
      15773745..15796516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036384225.2XP_036240118.1  tyrosine 3-monooxygenase

      UniProtKB/TrEMBL
      A0A7L3UZY5
      Related
      ENSMRTP00000020894.1
      Conserved Domains (3) summary
      pfam00351
      Location:158488
      Biopterin_H; Biopterin-dependent aromatic amino acid hydroxylase
      pfam12549
      Location:226
      TOH_N; Tyrosine hydroxylase N terminal
      cl09141
      Location:38153
      ACT; ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme