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    Ranbp16 Ranbp16 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 118436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ranbp16provided by FlyBase
    Official Full Name
    Ranbp16provided by FlyBase
    Primary source
    FLYBASE:FBgn0053180
    Locus tag
    Dmel_CG33180
    See related
    AllianceGenome:FB:FBgn0053180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33180; CG9126; CG9136; Dmel\CG33180; RanBP16
    Summary
    Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. Is expressed in adult head. Orthologous to human RANBP17 (RAN binding protein 17) and XPO7 (exportin 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ranbp16 in Genome Data Viewer
    Location:
    14A1-14A1; 1-52 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15927185..15933867, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15821218..15827900, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45000 Neighboring gene Ligand-gated chloride channel homolog 3 Neighboring gene Stromal interaction molecule Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Chan WM, et al. Hum Mol Genet, 2011 May 1. PMID 21300695
    2. Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins. Funikov SY, et al. Sci Rep, 2020 Jul 17. PMID 32681087, Free PMC Article
    3. Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing. Mazloomian A, et al. RNA Biol, 2015. PMID 26512413, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nuclear export signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear export signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nuclear export signal receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nuclear transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein export from nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Ranbp16
    Names
    CG33180-PB
    CG33180-PC
    CG33180-PE
    CG33180-PF
    CG33180-PG
    CG33180-PH
    Ranbp16-PB
    Ranbp16-PC
    Ranbp16-PE
    Ranbp16-PF
    Ranbp16-PG
    Ranbp16-PH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15927185..15933867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201666.2 → NP_001188595.1  Ranbp16, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188595.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MS57
      Conserved Domains (1) summary
      pfam03810
      Location:25 → 87
      IBN_N; Importin-beta N-terminal domain

    2. NM_001298379.1 → NP_001285308.1  Ranbp16, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285308.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5BI24, Q9GQN0, Q9VXL6, Q9VXL7
      UniProtKB/TrEMBL
      X2JFC3
      Conserved Domains (1) summary
      pfam03810
      Location:25 → 87
      IBN_N; Importin-beta N-terminal domain

    3. NM_176740.4 → NP_788913.2  Ranbp16, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788913.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5BI24, Q9GQN0, Q9VXL6, Q9VXL7
      UniProtKB/TrEMBL
      X2JFC3
      Related
      FBpp0089083
      Conserved Domains (1) summary
      pfam03810
      Location:25 → 87
      IBN_N; Importin-beta N-terminal domain

    4. NM_001201667.2 → NP_001188596.1  Ranbp16, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188596.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSD3
      Conserved Domains (1) summary
      pfam03810
      Location:25 → 87
      IBN_N; Importin-beta N-terminal domain

    5. NM_001201665.2 → NP_001188594.1  Ranbp16, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188594.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSN9
      Conserved Domains (1) summary
      pfam03810
      Location:25 → 87
      IBN_N; Importin-beta N-terminal domain

    6. NM_001201668.2 → NP_001188597.1  Ranbp16, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188597.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSB0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9MS57 M9MS57
    M9MSB0 M9MSB0
    M9MSD3 M9MSD3
    M9MSN9 M9MSN9
    Q9GQN0.1 Q9GQN0
    X2JFC3 X2JFC3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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