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    LOC115045486 collagen alpha-6(VI) chain-like [ Echeneis naucrates (live sharksucker) ]

    Gene ID: 115045486, updated on 21-Dec-2023

    Summary

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    Gene symbol
    LOC115045486
    Gene description
    collagen alpha-6(VI) chain-like
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Echeneis naucrates
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Carangiformes; Echeneidae; Echeneis
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    Genomic context

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    See LOC115045486 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    100 current fEcheNa1.1 (GCF_900963305.1) 6 NC_042516.1 (24129819..24166372)

    Chromosome 6 - NC_042516.1Genomic Context describing neighboring genes Neighboring gene collagen alpha-6(VI) chain-like Neighboring gene sorcin Neighboring gene phosphoinositide-3-kinase, regulatory subunit 4 Neighboring gene ATPase secretory pathway Ca2+ transporting 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_042516.1 Chromosome 6 Reference fEcheNa1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent conferring tensile strength IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    collagen alpha-6(VI) chain-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Echeneis naucrates Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fEcheNa1.1 Primary Assembly

    Genomic

    1. NC_042516.1 Reference fEcheNa1.1 Primary Assembly

      Range
      24129819..24166372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029505204.1 → XP_029361064.1  collagen alpha-6(VI) chain-like isoform X1

      Conserved Domains (7) summary
      pfam01391
      Location:2053 → 2112
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1631 → 1753
      VWA; von Willebrand factor (vWF) type A domain
      cd00109
      Location:2635 → 2687
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cd01472
      Location:33 → 198
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2708 → 2758
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1203 → 1373
      VWA; von Willebrand factor type A domain
      cl00057
      Location:236 → 399
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    2. XM_029505202.1 → XP_029361062.1  collagen alpha-6(VI) chain-like isoform X1

      Conserved Domains (7) summary
      pfam01391
      Location:2053 → 2112
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1631 → 1753
      VWA; von Willebrand factor (vWF) type A domain
      cd00109
      Location:2635 → 2687
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cd01472
      Location:33 → 198
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2708 → 2758
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1203 → 1373
      VWA; von Willebrand factor type A domain
      cl00057
      Location:236 → 399
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    3. XM_029505205.1 → XP_029361065.1  collagen alpha-6(VI) chain-like isoform X2

      Conserved Domains (6) summary
      pfam01391
      Location:2053 → 2112
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1631 → 1753
      VWA; von Willebrand factor (vWF) type A domain
      cd01472
      Location:33 → 198
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2651 → 2701
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1203 → 1373
      VWA; von Willebrand factor type A domain
      cl00057
      Location:236 → 399
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    4. XM_029505207.1 → XP_029361067.1  collagen alpha-6(VI) chain-like isoform X3

      Conserved Domains (7) summary
      pfam01391
      Location:1850 → 1909
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1428 → 1550
      VWA; von Willebrand factor (vWF) type A domain
      cd00109
      Location:2432 → 2484
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cd01472
      Location:626 → 787
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2505 → 2555
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1000 → 1170
      VWA; von Willebrand factor type A domain
      cl00057
      Location:33 → 196
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    5. XM_029505203.1 → XP_029361063.1  collagen alpha-6(VI) chain-like isoform X1

      Conserved Domains (7) summary
      pfam01391
      Location:2053 → 2112
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1631 → 1753
      VWA; von Willebrand factor (vWF) type A domain
      cd00109
      Location:2635 → 2687
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cd01472
      Location:33 → 198
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2708 → 2758
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1203 → 1373
      VWA; von Willebrand factor type A domain
      cl00057
      Location:236 → 399
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    6. XM_029505206.1 → XP_029361066.1  collagen alpha-6(VI) chain-like isoform X3

      Conserved Domains (7) summary
      pfam01391
      Location:1850 → 1909
      Collagen; Collagen triple helix repeat (20 copies)
      smart00327
      Location:1428 → 1550
      VWA; von Willebrand factor (vWF) type A domain
      cd00109
      Location:2432 → 2484
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cd01472
      Location:626 → 787
      vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
      pfam00014
      Location:2505 → 2555
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00092
      Location:1000 → 1170
      VWA; von Willebrand factor type A domain
      cl00057
      Location:33 → 196
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
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