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    LOC113322770 methyltetrahydroprotoberberine 14-monooxygenase [ Papaver somniferum (opium poppy) ]

    Gene ID: 113322770, updated on 3-Dec-2024

    Summary

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    Gene symbol
    LOC113322770
    Gene description
    methyltetrahydroprotoberberine 14-monooxygenase
    Locus tag
    C5167_047542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Papaver somniferum
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae; Papaver
    Also known as
    MSH; PsMSH; CYP82N4
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    Genomic context

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    See LOC113322770 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    100 current ASM357369v1 (GCF_003573695.1) 11 NC_039368.1 (128391320..128393637)

    Chromosome 11 - NC_039368.1Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase SDR family member 12-like Neighboring gene methyltetrahydroprotoberberine 14-monooxygenase-like Neighboring gene bifunctional protein STORR-like Neighboring gene protein DETOXIFICATION 27-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_039368.1 Chromosome 11 Reference ASM357369v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of a cDNA encoding (S)-cis-N-methylstylopine 14-hydroxylase from opium poppy, a key enzyme in sanguinarine biosynthesis. Beaudoin GA, et al. Biochem Biophys Res Commun, 2013 Feb 15. PMID 23313486
    2. Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. Zulak KG, et al. Planta, 2007 Apr. PMID 17077972
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to other organism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methyltetrahydroprotoberberine 14-monooxygenase
    Names
    (S)-cis-N-methylstylopine 14-hydroxylase
    (S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase
    Methyltetrahydroprotoberberine 14-hydroxylase
    N-methylstylopine hydroxylase
    cytochrome P450 82N4
    XP_026426700.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001426628.1 → NP_001413557.1  methyltetrahydroprotoberberine 14-monooxygenase

      Status: VALIDATED

      Source sequence(s)
      FE965458, FE968082, KC154003
      UniProtKB/Swiss-Prot
      L7X3S1
      UniProtKB/TrEMBL
      A0A4Y7LJV7

    RefSeqs of Annotated Genomes: Papaver somniferum Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM357369v1 Primary Assembly

    Genomic

    1. NC_039368.1 Reference ASM357369v1 Primary Assembly

      Range
      128391320..128393637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026570915.1 → XP_026426700.1  methyltetrahydroprotoberberine 14-monooxygenase

      Conserved Domains (1) summary
      cl12078
      Location:8 → 513
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    L7X3S1.1 GenPept UniProtKB/Swiss-Prot:L7X3S1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases