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    KLHL3 kelch like family member 3 [ Apteryx rowi (Okarito brown kiwi) ]

    Gene ID: 112964710, updated on 15-Mar-2024

    Summary

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    Gene symbol
    KLHL3
    Gene description
    kelch like family member 3
    See related
    Ensembl:ENSARWG00000002293
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Apteryx rowi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Apterygiformes; Apterygidae; Apteryx
    Orthologs
    human mouse all
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    Genomic context

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    See KLHL3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    100 current aptRow1 (GCF_003343035.1) Unplaced Scaffold NW_020448307.1 (5465701..5527281, complement)

    NW_020448307.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily C member 7 Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 Neighboring gene neuropeptide Y receptor type 6-like Neighboring gene myotilin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020448307 Unplaced Scaffold Reference aptRow1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in renal sodium ion absorption IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Apteryx rowi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference aptRow1

    Genomic

    1. NW_020448307.1 Reference aptRow1

      Range
      5465701..5527281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026063161.1 → XP_025918946.1  kelch-like protein 3 isoform X2

      Conserved Domains (4) summary
      PHA03098
      Location:372 → 888
      PHA03098; kelch-like protein; Provisional
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:753 → 798
      Kelch; KELCH repeat [structural motif]

    2. XM_026063162.1 → XP_025918947.1  kelch-like protein 3 isoform X3

      Conserved Domains (4) summary
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:660 → 703
      Kelch; KELCH repeat [structural motif]
      cl28614
      Location:373 → 885
      BTB; Broad-Complex, Tramtrack and Bric a brac

    3. XM_026063160.1 → XP_025918945.1  kelch-like protein 3 isoform X1

      Related
      ENSARWP00000003036.1, ENSARWT00000003554.1
      Conserved Domains (4) summary
      PHA03098
      Location:373 → 889
      PHA03098; kelch-like protein; Provisional
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:754 → 799
      Kelch; KELCH repeat [structural motif]

    4. XM_026063163.1 → XP_025918948.1  kelch-like protein 3 isoform X4

      Related
      ENSARWP00000003037.1, ENSARWT00000003555.1
      Conserved Domains (4) summary
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:707 → 765
      Kelch; KELCH repeat [structural motif]
      cl28614
      Location:373 → 855
      BTB; Broad-Complex, Tramtrack and Bric a brac

    5. XM_026063168.1 → XP_025918953.1  kelch-like protein 3 isoform X8

      Conserved Domains (2) summary
      PHA03098
      Location:58 → 574
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:439 → 484
      Kelch; KELCH repeat [structural motif]

    6. XM_026063166.1 → XP_025918951.1  kelch-like protein 3 isoform X7

      Conserved Domains (2) summary
      PHA03098
      Location:138 → 654
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:519 → 564
      Kelch; KELCH repeat [structural motif]

    7. XM_026063167.1 → XP_025918952.1  kelch-like protein 3 isoform X8

      Conserved Domains (2) summary
      PHA03098
      Location:58 → 574
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:439 → 484
      Kelch; KELCH repeat [structural motif]

    8. XM_026063173.1 → XP_025918958.1  kelch-like protein 3 isoform X12

      Conserved Domains (3) summary
      PHA03098
      Location:22 → 484
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:349 → 394
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:65 → 194
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    9. XM_026063171.1 → XP_025918956.1  kelch-like protein 3 isoform X10

      Conserved Domains (2) summary
      sd00038
      Location:360 → 405
      Kelch; KELCH repeat [structural motif]
      cl28614
      Location:33 → 495
      BTB; Broad-Complex, Tramtrack and Bric a brac

    10. XM_026063177.1 → XP_025918962.1  kelch-like protein 3 isoform X12

      Conserved Domains (3) summary
      PHA03098
      Location:22 → 484
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:349 → 394
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:65 → 194
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    11. XM_026063174.1 → XP_025918959.1  kelch-like protein 3 isoform X12

      Conserved Domains (3) summary
      PHA03098
      Location:22 → 484
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:349 → 394
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:65 → 194
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    12. XM_026063170.1 → XP_025918955.1  kelch-like protein 3 isoform X9

      Conserved Domains (3) summary
      PHA03098
      Location:3 → 506
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:371 → 416
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:87 → 216
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    13. XM_026063176.1 → XP_025918961.1  kelch-like protein 3 isoform X12

      Conserved Domains (3) summary
      PHA03098
      Location:22 → 484
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:349 → 394
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:65 → 194
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    14. XM_026063175.1 → XP_025918960.1  kelch-like protein 3 isoform X12

      Conserved Domains (3) summary
      PHA03098
      Location:22 → 484
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:349 → 394
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:65 → 194
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    15. XM_026063172.1 → XP_025918957.1  kelch-like protein 3 isoform X11

      Conserved Domains (2) summary
      sd00038
      Location:357 → 402
      Kelch; KELCH repeat [structural motif]
      cl28614
      Location:30 → 492
      BTB; Broad-Complex, Tramtrack and Bric a brac

    16. XM_026063164.1 → XP_025918949.1  kelch-like protein 3 isoform X5

      Conserved Domains (5) summary
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:620 → 656
      Kelch; KELCH repeat [structural motif]
      pfam07707
      Location:475 → 575
      BACK; BTB And C-terminal Kelch
      cl28614
      Location:373 → 755
      BTB; Broad-Complex, Tramtrack and Bric a brac

    17. XM_026063165.1 → XP_025918950.1  kelch-like protein 3 isoform X6

      Conserved Domains (6) summary
      smart00612
      Location:672 → 717
      Kelch; Kelch domain
      cd12326
      Location:5 → 83
      RRM1_hnRNPA0; RNA recognition motif 1 found in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      cd12579
      Location:99 → 178
      RRM2_hnRNPA0; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) and similar proteins
      sd00038
      Location:620 → 656
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:363 → 470
      BTB; BTB/POZ domain
      pfam07707
      Location:475 → 575
      BACK; BTB And C-terminal Kelch
    Nucleotide Protein
    Heading Accession and Version

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