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    ORC1 origin recognition complex subunit 1 [ Theropithecus gelada (gelada) ]

    Gene ID: 112628475, updated on 15-Mar-2024

    Summary

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    Gene symbol
    ORC1
    Gene description
    origin recognition complex subunit 1
    See related
    Ensembl:ENSTGEG00000005216
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Theropithecus gelada
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
    Orthologs
    human mouse all
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    Genomic context

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    See ORC1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current Tgel_1.0 (GCF_003255815.1) 1 NC_037668.1 (80258406..80290203, complement)

    Chromosome 1 - NC_037668.1Genomic Context describing neighboring genes Neighboring gene zinc finger FYVE-type containing 9 Neighboring gene anaphase-promoting complex subunit 10 pseudogene Neighboring gene coiled-coil and C2 domain containing 1B Neighboring gene small nucleolar RNA U13 Neighboring gene pre-mRNA processing factor 38A Neighboring gene terminal uridylyl transferase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037668.1 Chromosome 1 Reference Tgel_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA replication origin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic DNA replication checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    origin recognition complex subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tgel_1.0 Primary Assembly

    Genomic

    1. NC_037668.1 Reference Tgel_1.0 Primary Assembly

      Range
      80258406..80290203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025391254.1 → XP_025247039.1  origin recognition complex subunit 1

      UniProtKB/TrEMBL
      A0A8D2EH67
      Related
      ENSTGEP00000006356.1, ENSTGET00000007664.1
      Conserved Domains (3) summary
      cd08768
      Location:770 → 853
      Cdc6_C; Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding
      cd04719
      Location:44 → 170
      BAH_Orc1p_animal; BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC ...
      cl26671
      Location:494 → 742
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version

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