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    TRAF2 TNF receptor associated factor 2 [ Cyanistes caeruleus (blue tit) ]

    Gene ID: 111936895, updated on 3-Aug-2024

    Summary

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    Gene symbol
    TRAF2
    Gene description
    TNF receptor associated factor 2
    See related
    Ensembl:ENSCCEG00000023102
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cyanistes caeruleus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Paridae; Cyanistes
    Orthologs
    human mouse all
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    Genomic context

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    See TRAF2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    100 current cyaCae2 (GCF_002901205.1) 17 Unlocalized Scaffold NW_019776507.1 (228760..246375, complement)

    NW_019776507.1Genomic Context describing neighboring genes Neighboring gene complement C8 gamma chain Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene endothelial differentiation related factor 1 Neighboring gene MAM domain containing 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_019776507 Chromosome 17 Unlocalized Scaffold Reference cyaCae2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of plasma membrane signaling receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TNF receptor-associated factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cyanistes caeruleus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference cyaCae2

    Genomic

    1. NW_019776507.1 Reference cyaCae2

      Range
      228760..246375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023938005.1 → XP_023793773.1  TNF receptor-associated factor 2 isoform X2

      Conserved Domains (4) summary
      pfam02176
      Location:140 → 193
      zf-TRAF; TRAF-type zinc finger
      cl02446
      Location:318 → 481
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:251 → 313
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
      cd16639
      Location:69 → 110
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

    2. XM_023938004.1 → XP_023793772.1  TNF receptor-associated factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0VMH9
      Related
      ENSCCEP00000026247.1, ENSCCET00000039089.1
      Conserved Domains (4) summary
      pfam02176
      Location:161 → 217
      zf-TRAF; TRAF-type zinc finger
      cl02446
      Location:342 → 505
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam16673
      Location:275 → 337
      TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
      cd16639
      Location:69 → 110
      RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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