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    Socs4 suppressor of cytokine signaling 4 [ Mus pahari (shrew mouse) ]

    Gene ID: 110325522, updated on 15-Mar-2024

    Summary

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    Gene symbol
    Socs4
    Gene description
    suppressor of cytokine signaling 4
    See related
    Ensembl:MGP_PahariEiJ_G0030181
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mus pahari
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Coelomys
    Orthologs
    human mouse all
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    Genomic context

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    See Socs4 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    101 current PAHARI_EIJ_v1.1 (GCF_900095145.1) 8 NC_034597.1 (38101610..38115918)

    Chromosome 8 - NC_034597.1Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 4A Neighboring gene GTP cyclohydrolase 1 Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like Neighboring gene galectin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_034597.1 Chromosome 8 Reference PAHARI_EIJ_v1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppressor of cytokine signaling 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mus pahari Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference PAHARI_EIJ_v1.1

    Genomic

    1. NC_034597.1 Reference PAHARI_EIJ_v1.1

      Range
      38101610..38115918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029541633.1 → XP_029397493.1  suppressor of cytokine signaling 4 isoform X1

      Conserved Domains (3) summary
      cd10385
      Location:307 → 407
      SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03738
      Location:416 → 471
      SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
      pfam12610
      Location:93 → 141
      SOCS; Suppressor of cytokine signalling

    2. XM_029541634.1 → XP_029397494.1  suppressor of cytokine signaling 4 isoform X2

      Conserved Domains (3) summary
      cd10385
      Location:272 → 372
      SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03738
      Location:381 → 436
      SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
      pfam12610
      Location:58 → 106
      SOCS; Suppressor of cytokine signalling

    3. XM_021203559.2 → XP_021059218.1  suppressor of cytokine signaling 4 isoform X2

      Related
      MGP_PahariEiJ_P0084465, MGP_PahariEiJ_T0084465.1
      Conserved Domains (3) summary
      cd10385
      Location:272 → 372
      SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03738
      Location:381 → 436
      SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
      pfam12610
      Location:58 → 106
      SOCS; Suppressor of cytokine signalling

    4. XM_029541635.1 → XP_029397495.1  suppressor of cytokine signaling 4 isoform X2

      Conserved Domains (3) summary
      cd10385
      Location:272 → 372
      SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03738
      Location:381 → 436
      SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
      pfam12610
      Location:58 → 106
      SOCS; Suppressor of cytokine signalling
    Nucleotide Protein
    Heading Accession and Version

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