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    DGKA diacylglycerol kinase alpha [ Coturnix japonica (Japanese quail) ]

    Gene ID: 107325737, updated on 18-Sep-2024

    Summary

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    Gene symbol
    DGKA
    Gene description
    diacylglycerol kinase alpha
    See related
    Ensembl:ENSCJPG00005001769
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Coturnix japonica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Perdicinae; Coturnix
    Orthologs
    human mouse all
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    Genomic context

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    See DGKA in Genome Data Viewer
    Location:
    chromosome: LGE22C19W28_E50C23
    Exon count:
    23
    Annotation release Status Assembly LG Location
    101 current Coturnix japonica 2.1 (GCF_001577835.2) LGE22C19W28_E50C23 NC_029544.1 (801183..807868)

    Linkage Group LGE22C19W28_E50C23 - NC_029544.1Genomic Context describing neighboring genes Neighboring gene tubulin alpha-1C chain Neighboring gene transmembrane protein 198-like Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_029544.1 Chromosome LGE22C19W28_E50C23 Reference Coturnix japonica 2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in diacylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diacylglycerol kinase alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Coturnix japonica Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Coturnix japonica 2.1 Primary Assembly

    Genomic

    1. NC_029544.1 Reference Coturnix japonica 2.1 Primary Assembly

      Range
      801183..807868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015886882.2 → XP_015742368.1  diacylglycerol kinase alpha

      UniProtKB/TrEMBL
      A0A8C2SPC4
      Related
      ENSCJPP00005001726.1, ENSCJPT00005002916.1
      Conserved Domains (8) summary
      smart00045
      Location:553 → 731
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:411 → 532
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      COG1597
      Location:411 → 741
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
      cd00029
      Location:206 → 255
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd00051
      Location:114 → 183
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00130
      Location:271 → 323
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      pfam13499
      Location:115 → 179
      EF-hand_7; EF-hand domain pair
      pfam14513
      Location:6 → 110
      DAG_kinase_N; Diacylglycerol kinase N-terminus
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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